Substituted oxime ethers, their preparation and their use for controlling pests and fungi

ABSTRACT

Substituted oxime ethers of the general formula I ##STR1## where R 1  is alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, cyanoalkyl, alkoxycarbonylalkyl, arylalkyl, heteroarylalkyl, arylalkenyl or aryloxyalkyl, the aromatic or heteroaromatic ring being substituted or unsubstituted, 
     R 2  and R 3  are hydrogen, alkyl, haloalkyl, alkoxy, haloalkoxy, halogen, cyano or nitro, 
     R 4  is hydrogen, alkyl, cycloalkyl, haloalkyl or aryl, the aromatic ring being substituted or unsubstituted, and 
     R 5  and R 6  are identical or different and each is hydrogen or alkyl, and 
     X is CH or N, and fungicides and pesticides containing these compounds.

The present invention relates to novel substituted oxime ethers of the general formula I ##STR2## where R¹ is C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₄ -alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₄ -alkyl, C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, aryl-C₁ -C₆ -alkyl, hetaryl-C₁ -C₆ -alkyl, aryl-C₃ -C₆ -alkenyl or aryloxy-C₁ -C₆ -alkyl, where the aromatic or heteroaromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₃ -C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ or C₂ -haloalkoxy, halogen, aryl or aryloxy,

R² and R³ are identical or different and are each hydrogen, C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro,

R⁴ is hydrogen, C₁ -C₆ -alkyl C₃ -C₆ -cycloalkyl, C₁ -C₂ -haloalkyl or aryl, where the aromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro,

R⁵ and R⁶ are identical or different and are each hydrogen or C₁ -C₄ -alkyl and

X is CH or N.

The invention also relates to methods and intermediates for producing compounds I, fungicides containing them, and their use, pesticides containing them, and the use of compounds of the general formula IA ##STR3## where R¹, R², R³, R⁴ and X have the meanings given in claim 1 and Z is NR⁵ R⁶ or OR⁷, where R⁵ and R⁶ have the above meanings and R⁷ is C₁ -C₄ -alkyl, for controlling pests.

It is known that oxime ethers, for example methyl 2-(2'-methylphenoxymethyl)-phenylglyoxylate O-methyl oxime or methyl 2-(2'-methyl-4'-(methoximinoeth-1"-yl)phenoxymethyl)-phenylglyoxylate O-methyl oxime, can be used as fungicides (European Patents 253,213, 386,561 and 398,692).

Further, EP-A 386 561 discloses compounds of the formula IA, Z being methoxy, as fungicidal active ingredients.

It is an object of the invention to provide novel compounds having improved and wider applicability in crop protection.

We have found that this object is achieved by compounds I defined at the outset, methods and intermediates for producing them, agents containing them and the use thereof for controlling fungi, and agents for controlling fungi and the use of compounds of the formula IA defined at the outset for controlling fungi.

In the general formulae I and IA,

R¹ may be, for example, C₁ -C₆ -alkyl (C₁ -C₄ -alkyl) (e.g. methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, isopentyl, sec-pentyl, tert-pentyl, neopentyl or hexyl), C₃ -C₆ -alkenyl (e.g. allyl, 2-butenyl, 3-butenyl, 1-methyl-2-propenyl or 2-methyl-2-propenyl), C₃ - or C₄ -alkynyl (e.g. propargyl or 2-butynyl), C₁ -C₆ -haloalkyl (e.g. 2-fluoroethyl), C₃ -C₆ -haloalkenyl (e.g. 3-chloroallyl), C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl (e.g. 2-methoxyethyl or 3-ethoxypropyl), C₃ -C₆ -cycloalkyl (e.g. cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl), C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl (e.g. cyclopropylmethyl or cyclohexylmethyl), cyano-C₁ -C₆ -alkyl (e.g. cyanomethyl or 3-cyanopropyl), C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl (e.g. ethoxycarbonylmethyl, tert-butoxycarbonylmethyl or tert-butoxycarbonylpropyl), aryl-(phenyl)-C₁ -C₆ -alkyl (e.g. benzyl, 2-phenylethyl, 3-phenylpropyl or 4-phenylbutyl), hetaryl-(pyridyl, thienyl) -C₁ -C₆ -alkyl (e.g. pyrid-3-ylmethyl or thien-2-ylmethyl), aryl-(phenyi) -C₃ -C₆ -alkenyl (e.g. 4-phenyl-2-butenyl or 4-phenyl-3-butenyl), or aryloxy-(phenoxy)-C₁ -C₆ -alkyl (e.g. phenoxymethyl, phenoxyethyl, phenoxypropyl, phenoxybutyl, naphthyloxymethyl or naphthyloxyethyl),

where the aromatic (phenyl) or heteroaromatic (pyridyl, thienyl) ring is unsubstituted or substituted by one or more, for example 1 to 5, in particular 1 to 3, of the following radicals:

C₁ -C₄ -alkyl (e.g. methyl, ethyl, propyl or butyl), C₁ - or C₂ -haloalkyl (e.g. trifluoromethyl or trichloromethyl), C₃ -C₆ -cycloalkyl (e.g. cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl), C₁ -C₄ -alkoxy (e.g. methoxy, ethoxy, propoxy or butoxy), C₁ - or C₂ -haloalkoxy (e.g. trifluoromethoxy), halogen (e.g. fluorine, chlorine or bromine), aryl (e.g. phenyl) or aryloxy (e.g. phenoxy),

R² and R³ may be identical or different and are each hydrogen, C₁ -C₄ -alkyl (e.g. methyl, ethyl, n-propyl, isopropyl or butyl), C₁ - or C₂ -haloalkyl (e.g. trifluoromethyl or trichloromethyl), C₁ -C₄ -alkoxy (e.g. methoxy, ethoxy, n-propoxy, isopropoxy or butoxy), C₁ - or C₂ -haloalkoxy (e.g. trifluoromethoxy), halogen (e.g. fluorine, chlorine, bromine or iodine), cyano or nitro,

R⁴ may be, for example, C₁ -C₆ -alkyl, (C₁ -C₄ -alkyl) (e.g. methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, isopentyl, sec-pentyl, tert-pentyl, neopentyl or hexyl) or aryl (e.g. phenyl), where the aromatic ring is unsubstituted or substituted by one or more, for example 1 to 5, in particular 1 to 3, of the following radicals: C₁ -C₄ -alkyl (e.g. methyl, ethyl, propyl or butyl), C₁ - or C₂ -haloalkyl (e.g. trifluoromethyl or trichloromethyl), C₁ -C₄ -alkoxy (e.g. methoxy, ethoxy, propoxy or butoxy), C₁ - or C₂ -haloalkoxy (e.g. difluoromethoxy or trifluoromethoxy), halogen (e.g. fluorine, chlorine, bromine or iodine), cyano or nitro, R⁵ and R⁶ may be identical or different and are each hydrogen or C₁ -C₄ -alkyl (e.g. methyl, ethyl, n-propyl, isopropyl or butyl), preferred compounds being those in which R⁵ is hydrogen and R⁶ is methyl,

X may be CH or N, and R⁷ may be C₁ -C₄ -alkyl as mentioned above, especially methyl.

--C(R⁴)═N--O--R¹ may be in the 2-, 3- or, preferably, 4-position on the phenyl radical relative to --O-CH₂ --.

Owing to the C═C or C═N double bonds, the novel compounds of the general formula I and IA may be obtained in the preparation as E/Z isomer mixtures. These may be separated into the individual components in a conventional manner, for example by crystallization or chromatography. Both the individual isomeric compounds and mixtures thereof are embraced by the invention and can be used as fungicides and pesticides. Regarding the group --C(CONR⁵ R⁶)═X--OCH₃, preferred compounds are those in which CONR⁵ R⁶ and OCH₃ at the C═X double bond have the E configuration. Regarding the group --C(R⁴)═N--OR¹, preferred compounds are those in which R⁴ and OR¹ on the C═N double bond have the cis configuration and in which the C═N double bond therefore has the E configuration in the case of small substituents, e.g. methyl.

The novel compounds of the formula I are prepared, for example, by reacting a substituted oxime ether of the general formula II, where L is C₁ -C₄ -alkoxy, hydroxyl or halogen, such as chlorine or bromine, with a primary or secondary amine of the formula HNR⁵ R⁶. ##STR4##

Compounds of the formula II where L is C₁ -C₄ -alkoxy are disclosed in European Patent 386,561 or can be prepared by processes similar to those described there. The corresponding carboxylic acids II (L═OH) can be readily prepared therefrom by conventional processes (cf. for example Houben-Weyl, Vol. E 5, pages 223-254; Org. Reactions 24 (1976), 187-224). These can then be converted into activated carboxylic acid derivatives, examples being imidazolides II in which n is imidazol-1-yl or the acyl halides II in which n is C₁ or Br (cf. for example Houben-Weyl, Vol. VIII, page 463 et seq.). Reaction of the compounds of the formula II with primary or secondary amines HNR⁵ R⁶ gives the corresponding amides of the general formula I (cf. for example Houben-Weyl, Vol. E 5, pages 941-977 and 983-991; Houben Weyl, Vol. VIII, page 654 et seq.).

R¹, R², R³, R⁴, R⁵, R⁶ and X have the abovementioned meanings.

Compounds of the formula IA where Z is OR⁷ are known from EP-A 386,561 or may be produced by the methods described therein.

The Examples and methods which follow illustrate the preparation of the novel active ingredients and their intermediates.

PREPARATION EXAMPLE 1 N-Methyl-2-[2 '-methyl-4 '-(methoximinoeth-1"-yl)-phenoxymethyl]-phenylglyoxylamide O-methyl oxime

a) 225.3 g (1.5 mol) of 4-hydroxy-2-methylacetophenone are dissolved in 600 ml of dry methanol. 150.3 g (1.8 tool) of methoxyamine hydrochloride and 100 g of a molecular sieve are added. Stirring is carried out for 12 hours at room temperature (20° C.). The molecular sieve is filtered off. The filtrate is evaporated down. The remaining residue is taken up in dichloromethane. The organic phase is washed with water, dried and evaporated down. The solid product obtained is washed with pentane and then dried. 252 g (94%) of 4-hydroxy-2-methylacetophenone O-methyl oxime are obtained in the form of a colorless crystalline solid (mp.=96°-98° C.).

b) 89.6 g (0.5 tool) of 4-hydroxy-2-methylacetophenone O-methyl oxime in 300 ml of dry methanol are initially taken under nitrogen. 90 g (0.5 mol) of a 30% strength by weight sodium methylate solution are added dropwise. After 2 hours, the methanol is distilled off. The residue is dissolved in 700 ml of dimethylformamide. 15 g of potassium iodide are added. A solution of 151.6 g (0.53 mol) of methyl 2-(bromomethyl)-phenylglyoxylate O-methyl oxime in 300 ml of methanol are then added dropwise at room temperature under nitrogen. Stirring is carried out for about 10 hours at room temperature, after which the mixture is cooled to about 10° C. and water is added dropwise. The precipitate formed is filtered off, washed with water and pentane and dried. 153.7 g (80%) of methyl 2-[2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl]-phenylglyoxylate O-methyl oxime are obtained as a colorless crystalline solid (mp.: 138°-140° C.).

c) 4.8 g (0.012 mol) of methyl 2-[2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl]-phenylglyoxylate O-methyl oxime are dissolved in 32 ml of tetrahydrofuran, and 3.6 g (0.047 mol) of a 40% strength aqueous methylamine solution are added. Thereafter, the reaction mixture is stirred for 6 hours at 40° C. and then evaporated down. The residue was taken up in methyl tert-butyl ether. The organic phase is washed with water, dried and evaporated down again. The remaining crude product is purified by chromatography over a silica gel column (1:1 cyclohexane/ethyl acetate). 3.2 g (67%) of N-methyl-2-[2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl]phenylglyoxylamide O-methyl oxime are obtained in the form of colorless crystals (mp.: 104°-105° C., compound No. I.007).

PREPARATION EXAMPLE 2 N-Methyl-α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-β-methoxyacrylamide

a) Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate and 4-hydroxy-2-methylacetophenone O-methyl oxime are reacted similarly to Method b) (Example 1) to give methyl α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacrylate. The compound is obtained as a colorless solid (mp.: 118°-120° C.).

b) 3 g (0.0078 mol) of methyl α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacrylate are dissolved in 15 ml of dry pyridine. 5.2 g (0. 039 mol) of anhydrous lithium iodide are added and stirring is carried out for 8 hours at 130° C. The reaction mixture is evaporated down. The residue is taken up in water. The aqueous phase is first washed with methyl tert-butyl ether and then acidified with hydrochloric acid. The aqueous phase is then extracted with methyl tert-butyl ether. The methyl tert-butyl ether phase is washed with water, dried over sodium sulfate and evaporated down. 2.1 g of α-[2-(2 '-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-β-methoxyacrylic acid are obtained as a dark resin, which is used for the subsequent reactions without further purification.

c) 2.1 g (0.0056 mol) of α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl) -phenoxymethyl)-phenyl]-β-methoxyacrylic acid and 0.53 g of pyridine in 10 ml of dried diethyl ether are initially taken. 0.8 g (0.0067 mol) of thionyl chloride is added dropwise at 0°-5° C. and stirring is carried out for 10 hours at room temperature. The mixture is filtered. The filtrate is evaporated down. 2 g of α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-.beta.-methoxyacryloyl chloride are obtained as a dark oil, which is used for the subsequent reactions without further purification.

d) 1 g (0.0026 mol) of α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl) -phenoxymethyl)-phenyl]-β-methoxyacryloyl chloride in 10 ml of dichloromethane is initially taken. A solution of 1 g (0.032 mol) of methylamine in 10 ml of dichloromethane is added dropwise at 0°-5° C. Stirring is carried out for 10 hours at room temperature. The reaction mixture is taken up in 20 ml of dichloromethane and the solution is washed with water, dried and evaporated down. The remaining crude product is purified by chromatography over a silica gel column (2:1 n-hexane/acetone). 0.5 g (50%) of N-methyl-α-[2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)-phenyl]-β-methoxyacrylamide is obtained in the form of colorless crystals (mp.: 96°-98° C., compound No. I.006).

Compounds I (and IA in which Z is NR⁵ R⁶) listed in the Table below may be prepared similarly. Compounds IA where Z is OR⁷ may be obtained in accordance with the details given in EP-A 386,561. They too are listed in the Table below.

Compounds I (and IA in which Z is NR⁵ R⁶) of particular significance with regard to their biological action on pests (plant-pathogenic fungi, and insects, mites and nematodes) are listed in Tables 1, 2, 5-11 and 18-22 which follow.

Further, compounds IA in which Z is OR⁷ which are of particular significance with regard to their biological action on animal pests (insects, mites and nematodes) are listed in Tables 3, 4, 12-17 and 23-27.

    __________________________________________________________________________      ##STR5##                                                    IA                No.                                                                               R.sup.1     R.sup.2                                                                               R.sup.3                                                                             P*                                                                               R.sup.4                                                                               Z       X   Phys. data                     __________________________________________________________________________     I.001                                                                             CH.sub.3    H      H    3 CH.sub.3                                                                              NHCH.sub.3                                                                             N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            2.19(s, 3H);                                                                   2.86(d, 3H); 3.93(s,                                                           3H);                                                                           3.99(s, 3H); 4.95(s,                                                           2H);                                                                           6.7(sbr, 1H),                                                                  6.84-7.52(m, 8H)               I.002                                                                             C.sub.2 H.sub.5                                                                            H      H    3 CH.sub.3                                                                              NHCH.sub.3                                                                             N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            1.13(t, 3H);                                                                   2.29(s, 3H); 2.85(d,                                                           3H);                                                                           3.93(s, 3H); 4.23(q,                                                           2H);                                                                           4.96(s, 2H); 6.75(sbr,                                                         1H);                                                                           6.86-7.55(m, 8H)               I.003                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    3 CH.sub.3                                                                              NHCH.sub.3                                                                             N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            2.2(d, 3H);                                                                    2.86(d, 3H); 3.92(s,                                                           3H);                                                                           4.69(m, 2H); 4.96(s,                                                           2H);                                                                           5.17-5.38(m, 2H);                                                              5.96-6.17(m, 1H);                                                              6.37(sbr, 1H);                                                                 6.84-7.54(m, 8H)               I.004                                                                             CH(CH.sub.3).sub.2                                                                         H      H    3 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 101-103° C.                                                         (E; E)                         I.005                                                                             CH.sub.3    2-Cl   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 123-124° C.                                                         (E; E)                         I.006                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             CH  mp: 96-98° C. (E;                                                       E)                             I.007                                                                             CH.sub.3    2-CH.sub. 3                                                                           H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 104-105° C.                                                         (E; E)                         I.008                                                                             CH.sub.3    2-OCH.sub.3                                                                           H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 78-80° C. (E;                                                       E)                             I.009                                                                             CH.sub.3    3-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 89-90° C. (E;                                                       E)                             I.010                                                                             C.sub.2 H.sub.5                                                                            2-Cl   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 107-108° C.                                                         (E; E)                         I.011                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 92-94° C. (E;                                                       E)                             I.012                                                                             C.sub.2 H.sub.5                                                                            2-OCH.sub.3                                                                           H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 78-81° C. (E;                                                       E)                             I.013                                                                             C.sub.2 H.sub.5                                                                            3-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   resin (E; E)                   I.014                                                                             CH.sub.3    2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            2.13(s, 3H);                                                                   2.18(s, 3H); 2.28(s,                                                           3H);                                                                           2.87(d, 3H); 3.95("s",                                                         6H);                                                                           4.92(s, 2H); 6.61(s,                                                           1H);                                                                           6.72(sbr, 1H); 7.00(s,                                                         1H);                                                                           7.19-7.56(m, 4H)               I.015                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            1.1(t, 3H);                                                                    2.23(s, 3H); 2.7(q, 2H);                                                       2.86(d, 3H); 3.93(s,                                                           3H);                                                                           3.96(s, 3H)4.98(s, 2H);                                                        6.72(sbr, 1H);                                                                 6.75-7.55(m, 7H)               I.016                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 98-106° C. (E;                                                      E)                             I.017                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   resin (E; E)                                                                   .sup.1 H-NMR (ppm):                                                            1.3(t, 3H);                                                                    2.15(s, 3H); 2.17(s,                                                           3H);                                                                           2.29(s, 3H); 2.87(d,                                                           3H);                                                                           3.95(s, 3H); 4.18(q,                                                           2H);                                                                           4.94(s, 2H); 6.61(s,                                                           1H);                                                                           6.72(sbr, 1H); 6.99(s,                                                         1H);                                                                           7.2-7.57(m, 4H)                I.018                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 72-73° C. (E;                                                       E)                             I.019                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 54-56° C. (E;                                                       E)                             I.020                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 96-98° C. (E;                                                       E)                             I.021                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 61-63° C. (E;                                                       E)                             I.022                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 49-52° C. (E;                                                       E)                             I.023                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 71-73° C. (E;                                                       E)                             I.024                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH(CH.sub.3).sub.2                                                                    NHCH.sub.3                                                                             N   resin (E; E)                   I.025                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 94-96° C. (E;                                                       E)                             I.026                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 76-79° C. (E;                                                       E)                             I.027                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 86-88° C. (E;                                                       E)                             I.028                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   resin (E; E)                   I.029                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.030                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 74-76° C. (E;                                                       E)                             I.031                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 87-89° C. (E;                                                       E)                             I.032                                                                             CH.sub.3    2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.033                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.034                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub. 3                                                                         4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 58-66° C. (E;                                                       E)                             I.035                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.036                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.037                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 58-60° C. (E;                                                       E)                             I.038                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 84-86° C. (E;                                                       E)                             I.039                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-Cl   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 92-94° C. (E;                                                       E)                             I.040                                                                             CH.sub.2 CHCH.sub.2                                                                        2-Cl   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 80-82° C. (E;                                                       E)                             I.041                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 (CH.sub.2).sub.2 CH.sub.3                                                             NHCH.sub.3                                                                             N   mp: 105-107° C.                                                         (E; E)                         I.042                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 52-54° C. (E;                                                       E)                             I.043                                                                             CH.sub.2 CCH                                                                               2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 142-144° C.                                                         (E; E)                         I.044                                                                             CH.sub.2 CCH                                                                               2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 88-90° C. (E;                                                       E)                             I.045                                                                             CH.sub.2 CCH                                                                               2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 99-101° C. (E;                                                      E)                             I.046                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 67-69° C. (E;                                                       E)                             I.047                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       NHCH.sub.3                                                                             N   mp: 108-110° C.                                                         (E; E)                         I.048                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 110-112° C.                                                         (E; E)                         I.049                                                                             CH.sub.2 CN 2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 114-116° C.                                                         (E; E)                         I.050                                                                             CH.sub.2 CN 2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 104-106° C.                                                         (E; E)                         I.051                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 C.sub.6 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.052                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.6 H.sub.5                                                                       NHCH.sub.3                                                                             N   resin (E; E)                   I.053                                                                             CH.sub.3    H      H    2 H      OCH.sub.3                                                                              CH  mp: 82-84° C. (E;                                                       E)                             I.054                                                                             CH.sub.3    H      H    2 H      OCH.sub.3                                                                              N   mp: 73-76° C. (E;                                                       E)                             I.055                                                                             C.sub.2 H.sub.5                                                                            H      H    2 H      OCH.sub.3                                                                              CH  mp: 86-88° C. (E;                                                       E)                             I.056                                                                             C.sub.2 H.sub.5                                                                            H      H    2 H      OCH.sub.3                                                                              N   mp: 89-90° C. (E;                                                       E)                             I.057                                                                             C.sub.2 H.sub.5                                                                            4-Cl   H    2 H      OCH.sub.3                                                                              CH  mp: 95-97° C. (E;                                                       E)                             I.058                                                                             CH.sub.3    H      H    3 H      OCH.sub.3                                                                              CH  mp: 75-77° C. (E;                                                       E)                             I.059                                                                             CH.sub.3    H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.060                                                                             C.sub.2 H.sub.5                                                                            H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            1.28(t, 3H);                                                                   3.69(s, 3H); 3.73(s,                                                           3H);                                                                           4.20(q, 2H); 4.97(s,                                                           2H);                                                                           6.85-7.53(m, 8H);                                                              7.57(s, 1H); 8,0(s, 1H)        I.061                                                                             C.sub.2 H.sub.5                                                                            H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.062                                                                             C.sub.2 H.sub.5                                                                            6-OCH.sub.3                                                                           H    3 H      OCH.sub.3                                                                              CH  mp: 96-98° C. (E;                                                       E)                             I.063                                                                             C.sub.2 H.sub.5                                                                            6-OCH.sub.3                                                                           H    3 H      OCH.sub.3                                                                              N   mp: 124-126° C.                                                         (E; E)                         I.064                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.065                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.066                                                                             CH(CH.sub.3).sub.2                                                                         H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.067                                                                             CH(CH.sub.3).sub.2                                                                         H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.068                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.069                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.070                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.071                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.072                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.073                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.074                                                                             C.sub.2 H.sub.5                                                                            6-OC.sub.2 H.sub.5                                                                    H    3 H      OCH.sub.3                                                                              CH  mp: 83-85° C. (E;                                                       E)                             I.075                                                                             C.sub.2 H.sub.5                                                                            6-OC.sub.2 H.sub.5                                                                    H    3 H      OCH.sub.3                                                                              N   mp: 104-106° C.                                                         (E; E)                         I.076                                                                             (CH.sub.2).sub.4 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.077                                                                             CH.sub.2 -(2-FC.sub.6 H.sub.4)                                                             H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.078                                                                             CH.sub.2 -(2-FC.sub.6 H.sub.4)                                                             H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.079                                                                             CH.sub.2 -(3-FC.sub.6 H.sub.4)                                                             H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.080                                                                             CH.sub.2 -(3-FC.sub.6 H.sub.4)                                                             H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.081                                                                             CH.sub.2 -(2-ClC.sub.6 H.sub.4)                                                            H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.082                                                                             (3,4-Cl.sub.2C.sub.6 H.sub.3)                                                              H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                        CH.sub.2                                                                    I.083                                                                             (3,4-Cl.sub.2C.sub.6 H.sub.3)                                                              H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                        CH.sub.2                                                                    I.084                                                                             (2,6-Cl.sub.2C.sub.6 H.sub.3)                                                              H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                        CH.sub.2                                                                    I.085                                                                             (2,6-Cl.sub.2C.sub.6 H.sub.3)                                                              H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                        CH.sub.2                                                                    I.086                                                                             (CH.sub.2).sub.2 C.sub.6 H.sub.5                                                           H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.087                                                                             (CH.sub.2).sub.2 C.sub.6 H.sub.5                                                           H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.088                                                                             (CH.sub.2).sub.2 CHCHC.sub.6 H.sub.5                                                       H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.089                                                                             (CH.sub.2).sub.2 CHCHC.sub.6 H.sub.5                                                       H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                     I.090                                                                             (4-ClC.sub.6 H.sub.4)                                                                      H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                        CH.sub.2 CH CHCH.sub.2                                                      I.091                                                                             (4-ClC.sub.6 H.sub.4)                                                                      H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                        CH.sub.2 CHCHCH.sub.2                                                       I.092                                                                             (4-CF.sub.3C.sub.6 H.sub.4)                                                                H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                        CH.sub.2 CHCHCH.sub.2                                                       I.093                                                                             (4-CF.sub.3C.sub.6 H.sub.4)                                                                H      H    3 H      OCH.sub.3                                                                              N   oil (E; E)                        CH.sub.2 CHCHCH.sub.2                                                       I.094                                                                             CH.sub.3    H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.095                                                                             CH.sub.3    H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                     I.096                                                                             C.sub.2 H.sub.5                                                                            H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            1.32(t, 3H);                                                                   2.18(s, 3H); 3.68(s,                                                           3H);                                                                           3.77(s, 3H); 4.22(q,                                                           2H);                                                                           4.97(s, 2H);                                                                   6.83-7.53(m, 8H);                                                              7.55(s, 1H)                    I.097                                                                             C.sub.2 H.sub.5                                                                            H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            1.32(t, 3H);                                                                   2.17(s, 3H); 3.82(s,                                                           3H);                                                                           4.0(s, 3H); 4.23(q, 4H);                                                       4.97(s, 2H);                                                                   6.83-7.57(m, 8H)               I.098                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.099                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 73-74° C. (E;                                                       E)                             I.100                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.101                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 51-53° C. (E;                                                       E)                             I.102                                                                             CH(CH.sub.3).sub.2                                                                         H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.103                                                                             CH(CH.sub.3).sub.2                                                                         H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 58-60° C. (E;                                                       E)                             I.104                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.105                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            0.95(t, 3H);                                                                   1.43(m, 2H); 1.7(m, 2H);                                                       2.18(s, 3H); 3.83(s,                                                           3H);                                                                           4.0(s, 3H); 4.17(t, 2H);                                                       4.97(s, 2H);                                                                   6.82-7.55(m, 8H)               I.106                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.107                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 76-78° C. (E;                                                       E)                             I.108                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.109                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            0.87(t, 3H);                                                                   1.32(m, 6H); 1.7(m, 2H);                                                       2.18(s, 3H); 3.83(s,                                                           3H);                                                                           4.02(s, 3H); 4.17(t,                                                           2H);                                                                           4.95(s, 2H);                                                                   6.83-7.57(m, 8H)               I.110                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            2.22(s, 3H);                                                                   3.78(s, 3H); 4.0(s, 3H);                                                       4.97(s, 2H); 5.23(s,                                                           2H);                                                                           6.82-7.53(m, 8H)               I.111                                                                             CH.sub.2 CHCHCl                                                                            H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.112                                                                             CH.sub.2 CHCHCl                                                                            H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                     I.113                                                                             C(CH.sub.3).sub.2 CH.sub.3                                                                 H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.114                                                                             C(CH.sub.3).sub.2 CH.sub.3                                                                 H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 83-85° C. (E;                                                       E)                             I.115                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.116                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 70-72° C. (E;                                                       E)                             I.117                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.118                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 64-65° C. (E;                                                       E)                             I.119                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.120                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                     I.121                                                                             CH.sub.3    H      H    4 H      OCH.sub.3                                                                              CH  mp: 84-86° C. (E;                                                       E)                             I.122                                                                             CH.sub.3    H      H    4 H      OCH.sub.3                                                                              N   mp: 88-91° C. (E;                                                       E)                             I.123                                                                             CH.sub.3    2-OCH.sub.3                                                                           H    4 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.124                                                                             CH.sub.3    2-OCH.sub.3                                                                           H    4 H      OCH.sub.3                                                                              N   mp: 105-107° C.                                                         (E; E)                         I.125                                                                             C.sub.2 H.sub.5                                                                            H      H    4 H      OCH.sub.3                                                                              CH  mp: 108-110° C.                                                         (E; E)                         I.126                                                                             C.sub.2 H.sub.5                                                                            H      H    4 H      OCH.sub.3                                                                              N   mp: 106-108° C.                                                         (E; E)                         I.127                                                                             CH.sub. 2 CHCH.sub.2                                                                       H      H    4 H      OCH.sub.3                                                                              CH  mp: 103-105° C.                                                         (E; E)                         I.128                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    4 H      OCH.sub.3                                                                              N   mp: 82-84° C. (E;                                                       E)                             I.129                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    4 H      OCH.sub.3                                                                              CH  mp: 62-63° C. (E;                                                       E)                             I.130                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    4 H      OCH.sub.3                                                                              N   mp: 72-73° C. (E;                                                       E)                             I.131                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    4 H      OCH.sub.3                                                                              N   mp: 103-105° C.                                                         (E; E)                         I.132                                                                             CH.sub.2 -(4-ClC.sub.6 H.sub.4)                                                            H      H    4 H      OCH.sub.3                                                                              CH  mp: 151-153° C.                                                         (E; E)                         I.133                                                                             CH.sub.2 CHCHCl                                                                            H      H    4 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.134                                                                             CH.sub.2 CHCHCl                                                                            H      H    4 H      OCH.sub.3                                                                              N   mp: 95-97° C. (E;                                                       E)                             I.135                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    4 H      OCH.sub.3                                                                              CH  mp: 100-102° C.                                                         (E; E)                         I.136                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    4 H      OCH.sub.3                                                                              N   mp: 95-96° C. (E;                                                       E)                             I.137                                                                             (CH.sub.2).sub.4 CH.sub.3                                                                  H      H    4 H      OCH.sub.3                                                                              N   oil (E; E)                     I.138                                                                             CH.sub.3    H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.139                                                                             CH.sub.3    H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 99-100° C. (E;                                                      E)                             I.140                                                                             CH.sub.3    2-Cl   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 93-94° C. (E;                                                       E)                             I.141                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 137-139° C.                                                         (E; E)                         I.142                                                                             CH.sub.3    2-OCH.sub.3                                                                           H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 82-84° C. (E;                                                       E)                             I.143                                                                             CH.sub.3    3-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 55-56° C. (E;                                                       E)                             I.144                                                                             C.sub.2 H.sub.5                                                                            H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 71-73° C. (E;                                                       E)                             I.145                                                                             C.sub.2 H.sub.5                                                                            H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 79-80° C. (E;                                                       E)                             I.146                                                                             C.sub.2 H.sub.5                                                                            2-Cl   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 88-90° C. (E;                                                       E)                             I.147                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 109-111° C.                                                         (E; E)                         I.148                                                                             C.sub.2 H.sub.5                                                                            2-OCH.sub.3                                                                           H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 96-98° C. (E;                                                       E)                             I.149                                                                             C.sub.2 H.sub.5                                                                            3-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   resin (E; E)                   I.150                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 87-99° C. (E;                                                       E)                             I.151                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 100-101° C.                                                         (E; E)                         I.152                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 90-92° C. (E;                                                       E)                             I.153                                                                             CH.sub.2 CHCH.sub.2                                                                        H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 107-108° C.                                                         (E; E)                         I.154                                                                             CH(CH.sub.3).sub.2                                                                         H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 120-123° C.                                                         (E; E)                         I.155                                                                             CH(CH.sub.3).sub.2                                                                         H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 109-110° C.                                                         (E; E)                         I.156                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 64-66° C. (E;                                                       E)                             I.157                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                                                                     .sup.1 H-NMR (ppm):                                                            0.97(t, 3H);                                                                   1.4(m, 2H); 1.68(m, 2H);                                                       2.17(s, 3H); 3.83(s,                                                           3H);                                                                           4.0(s, 3H); 4.15(t, 2H);                                                       4.95(s, 2H);                                                                   6.82-7.57(m, 8H)               I.158                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.159                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 100-103° C.                                                         (E; E)                         I.160                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 65-67° C. (E;                                                       E)                             I.161                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 60-63° C. (E;                                                       E)                             I.162                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 110-112° C.                                                         (E; E)                         I.163                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 104-106° C.                                                         (E; E)                         I.164                                                                             CH.sub.2 CHCHCl                                                                            H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 98-100° C. (E;                                                      E)                             I.165                                                                             CH.sub.2 CHCHCl                                                                            H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 105-107° C.                                                         (E; E)                         I.166                                                                             C(CH.sub.3).sub.3                                                                          H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 88-90° C. (E;                                                       E)                             I.167                                                                             C(CH.sub.3).sub.3                                                                          H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 75-78° C. (E;                                                       E)                             I.168                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 85-87° C. (E;                                                       E)                             I.169                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 79-81° C. (E;                                                       E)                             I.170                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 94-96° C. (E;                                                       E)                             I.171                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 88-89° C. (E;                                                       E)                             I.172                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 46-48° C. (E;                                                       E)                             I.173                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        H      H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   oil (E; E)                     I.174                                                                             CH.sub.3    2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 104-107° C.                                                         (E; E)                         I.175                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 84-87° C. (E;                                                       E)                             I.176                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 78-80° C. (E;                                                       E)                             I.177                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 79-81° C. (E;                                                       E)                             I.178                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 88-89° C. (E;                                                       E)                             I.179                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 77-79° C. (E;                                                       E)                             I.180                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 65-68° C. (E;                                                       E)                             I.181                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 58-62° C. (E;                                                       E)                             I.182                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 69-71° C. (E;                                                       E)                             I.183                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 73-75° C. (E;                                                       E)                             I.184                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 44-45° C. (E;                                                       E)                             I.185                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 90-92° C. (E;                                                       E)                             I.186                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 85-87° C. (E;                                                       E)                             I.187                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 65-68° C. (E;                                                       E)                             I.188                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 92-93° C. (E;                                                       E)                             I.189                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 82-84° C. (E;                                                       E)                             I.190                                                                             CH.sub.3    2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 109-111° C.                                                         (E; E)                         I.191                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 87-89° C. (E;                                                       E)                             I.192                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 99-100° C. (E;                                                      E)                             I.193                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 83-85° C. (E;                                                       E)                             I.194                                                                             (CH.sub.2).sub.2 OCH.sub.3                                                                 2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 81-83° C. (E;                                                       E)                             I.195                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 81-83° C. (E;                                                       E)                             I.196                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 67-70° C. (E;                                                       E)                             I.197                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-Cl   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 66-68° C. (E;                                                       E)                             I.198                                                                             CH.sub.2 CHCH.sub.2                                                                        2-Cl   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 91-92° C. (E;                                                       E)                             I.199                                                                             CH.sub.2 CHCH                                                                              2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 107-109° C.                                                         (E; E)                         I.200                                                                             CH.sub.2 CHCH                                                                              2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 100-102° C.                                                         (E; E)                         I.201                                                                             CH.sub.2 CHCH                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 87-89° C. (E;                                                       E)                             I.202                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 118-120° C.                                                         (E; E)                         I.203                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 95-97° C. (E;                                                       E)                             I.204                                                                             CH.sub.2 CHCHCl                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 89-91° C. (E;                                                       E)                             I.205                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 C.sub.6 H.sub.5                                                                       OCH.sub.3                                                                              N   resin (E; E)                   I.206                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 C.sub.6 H.sub.5                                                                       OCH.sub.3                                                                              N   resin (E; E)                   I.207                                                                             CH.sub.2 CO.sub.2 C(CH.sub.3).sub.3                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   resin (E; E)                   I.208                                                                             (CH.sub.2).sub.3                                                                           2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 67-69° C. (E;                                                       E)                                CO.sub.2 C(CH.sub.3).sub.3                                                  I.209                                                                             (CH.sub.2).sub.4                                                                           2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 54-56° C. (E;                                                       E)                                CO.sub.2 C(CH.sub.3).sub.3                                                  I.210                                                                             (CH.sub.2).sub.4                                                                           2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                      CO.sub.2 C(CH.sub.3).sub.3                                                  I.211                                                                             (CH.sub.2).sub.5                                                                           2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 46-48° C. (E;                                                       E)                                CO.sub.2 C(CH.sub.3).sub.3                                                  I.212                                                                             (CH.sub.2).sub.5                                                                           2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 56-58° C. (E;                                                       E)                                CO.sub.2 C(CH.sub.3).sub.3                                                  I.213                                                                             CH.sub.2 CHCH                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   resin (E; E)                   I.214                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N   mp: 78-80° C. (E;                                                       E)                             I.215                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      CH  resin (E; E)                   I.216                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N   resin (E; E)                   I.217                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NH.sub.2                                                                               CH  mp: 143-144° C.                                                         (E; E)                         I.218                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              NHC.sub.2 H.sub.5                                                                      CH  mp: 110-111° C.                                                         (E; E)                         I.219                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              N(CH.sub.3)C.sub.2 H.sub.5                                                             CH  resin (E; E)                   I.220                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 c-C.sub.3 H.sub.5                                                                     NHCH.sub.3                                                                             N   .sup.1 H-NMR (ppm):                                                            0.6-2.79(m, 5H); 2.2(s,                                                        3H);                                                                           2.9(d, 3H); 3.9(s, 3H);                                                        3.95(s, 3H); 4.97(s,                                                           2H);                                                                           6.7-7.6(m, 6H)                 I.221                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 c-C.sub.3 H.sub.5                                                                     NHCH.sub.3                                                                             N   .sup.1 H-NMR (ppm):                                                            0.6-1.8(m, 8H); 2.2(s,                                                         3H);                                                                           2.88(d, 3H); 3.95(s,                                                           3H);                                                                           4.2(q, 2H); 4.93(s, 2H);                                                       6.7-7.6(m, 8H)                 I.222                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 c-C.sub.3 H.sub.5                                                                     NHCH.sub.3                                                                             N   .sup.1 H-NMR (ppm):                                                            0.6-1.78(m, 10H);                                                              2.2(s, 3H); 2.9(d, 3H);                                                        3.92(s, 3H); 4.1(t, 2H);                                                       4.97(s, 2H); 6.62-7.9(m,                                                       8H)                            I.223                                                                             CH.sub.3    2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 80-83° C. (E;                                                       E)                             I.224                                                                             C.sub.2 H.sub.5                                                                            2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 96-98° C. (E;                                                       E)                             I.225                                                                             CH.sub.3    2-Cl   5-Cl 4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 121-122° C.                                                         (E; E)                         I.226                                                                             C.sub.2 H.sub.5                                                                            2-Cl   5-Cl 4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 105-107° C.                                                         (E; E)                         I.227                                                                             CH.sub. 3   2-F    H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 80-81° C. (E;                                                       E)                             I.228                                                                             C.sub.2 H.sub.5                                                                            2-F    H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 63-64° C. (E;                                                       E)                             I.229                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-F    H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 86-87° C. (E;                                                       E)                             I.230                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-F    H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 49-51° C. (E;                                                       E)                             I.231                                                                             CH.sub.2 CHCH.sub.2                                                                        2-F    H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 82-83° C. (E;                                                       E)                             I.232                                                                             CH.sub.3    2-Br   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 136-138° C.                                                         (E; E)                         I.233                                                                             C.sub.2 H.sub.5                                                                            2-Br   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 115-117° C.                                                         (E; E)                         I.234                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Br   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 95-96° C. (E;                                                       E)                             I.235                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-Br   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 102-103° C.                                                         (E; E)                         I.236                                                                             CH.sub.2 CHCH.sub.2                                                                        2-Br   H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 119-120°  C.                                                        (E; E)                         I.237                                                                             CH.sub.3    2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 89-91° C. (E;                                                       E)                             I.238                                                                             C.sub.2 H.sub.5                                                                            2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 83-84° C. (E;                                                       E)                             I.239                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 87-88° C. (E;                                                       E)                             I.240                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 84-85° C. (E;                                                       E)                             I.241                                                                             CH.sub.2 CHCH.sub.2                                                                        2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 82-83° C. (E;                                                       E)                             I.242                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   5-Cl 4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 89-91° C. (E;                                                       E)                             I.243                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              NHCH.sub.3                                                                             N   mp: 85-86° C. (E;                                                       E)                             I.244                                                                             CH.sub.3    2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   resin (E; E)                   I.245                                                                             C.sub.2 H.sub.5                                                                            2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 65-67°  C. (E;                                                      E)                             I.246                                                                             CH.sub.3    2-Cl   5-Cl 4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 73-74° C. (E;                                                       E)                             I.247                                                                             C.sub.2 H.sub.5                                                                            2-Cl   5-Cl 4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 79-80° C. (E;                                                       E)                             I.248                                                                             CH.sub.3    2-F    H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 88-89° C. (E;                                                       E)                             I.249                                                                             C.sub.2 H.sub.5                                                                            2-F    H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 65-66° C. (E;                                                       E)                             I.250                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-F    H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 103-104° C.                                                         (E; E)                         I.251                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-F    H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 84-86° C. (E;                                                       E)                             I.252                                                                             CH.sub.2 CHCH.sub.2                                                                        2-F    H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 107-109° C.                                                         (E; E)                         I.253                                                                             CH.sub.3    2-Br   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 90-91° C. (E;                                                       E)                             I.254                                                                             C.sub.2 H.sub.5                                                                            2-Br   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 103-104° C.                                                         (E; E)                         I.255                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Br   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 86-87°  C. (E;                                                      E)                             I.256                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-Br   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 68-69° C. (E;                                                       E)                             I.257                                                                             CH.sub.2 CHCH.sub.2                                                                        2-Br   H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 96-97° C. (E;                                                       E)                             I.258                                                                             CH.sub.3    2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 64-66° C. (E;                                                       E)                             I.259                                                                             C.sub.2 H.sub.5                                                                            2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 56-57° C. (E;                                                       E)                             I.260                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 52-53° C. (E;                                                       E)                             I.261                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 40-41° C. (E;                                                       E)                             I.262                                                                             CH.sub.2 CHCH.sub.2                                                                        2-C.sub.2 H.sub.5                                                                     H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   resin (E; E)                   I.263                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   5-Cl 4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 80-81° C. (E;                                                       E)                             I.264                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-Cl   5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 56-58° C. (E;                                                       E)                             I.265                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    3 H      OCH.sub.3                                                                              CH  mp: 74-76° C. (E;                                                       E)                             I.266                                                                             CH.sub.2 CHCHCl                                                                            H      H    3 H      OCH.sub.3                                                                              CH  mp: 56-58° C. (E;                                                       E)                             I.267                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    3 H      OCH.sub.3                                                                              CH  mp: 52-54° C. (E;                                                       E)                             I.268                                                                             (CH.sub.2).sub.4 CH.sub.3                                                                  H      H    3 H      OCH.sub.3                                                                              CH  oil (E; E)                     I.269                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   H      H    3 CH.sub.3                                                                              OCH.sub.3                                                                              CH  oil (E; E)                     I.270                                                                             CH.sub.2 CHCHCH.sub.3                                                                      H      H    4 H      OCH.sub.3                                                                              CH  mp: 86-88° C. (E;                                                       E)                             I.271                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                H      H    4 H      OCH.sub.3                                                                              CH  mp: 97-99° C. (E;                                                       E)                             I.272                                                                             (CH.sub.2).sub.4 CH.sub.3                                                                  H      H    4 H      OCH.sub.3                                                                              CH  mp: 84-86° C. (E;                                                       E)                             I.273                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 118-120° C.                                                         (E; E)                         I.274                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 101-103°  C.                                                        (E; E)                         I.275                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 113-115° C.                                                         (E; E)                         I.276                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 113-115° C.                                                         (E; E)                         I.277                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 81-82° C. (E;                                                       E)                             I.278                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 80-81° C. (E;                                                       E)                             I.279                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 117-119° C.                                                         (E; E)                         I.280                                                                             CH.sub.2 CH(CH.sub.3).sub.2                                                                2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 91-93° C. (E;                                                       E)                             I.281                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 97-99° C. (E;                                                       E)                             I.282                                                                             C(CH.sub.3).sub.3                                                                          2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 83-85° C. (E;                                                       E)                             I.283                                                                             C(CH.sub.3).sub.3                                                                          2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 86-88° C. (E;                                                       E)                             I.284                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 106-108° C.                                                         (E; E)                         I.285                                                                             CH.sub.2 C(CH.sub.3)CH.sub.2                                                               2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 51-54° C. (E;                                                       E)                             I.286                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 72-74° C. (E;                                                       E)                             I.287                                                                             (CH.sub.2).sub.2 CH(CH.sub.3).sub.2                                                        2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 58-60° C. (E;                                                       E)                             I.288                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 76-78° C. (E;                                                       E)                             I.289                                                                             (CH.sub.2).sub.5 CH.sub.3                                                                  2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 78-80° C. (E;                                                       E)                             I.290                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 85-88° C. (E;                                                       E)                             I.291                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   2-CH.sub.3                                                                            H    4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 98-101° C. (E;                                                      E)                             I.292                                                                             CH.sub.3    2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub. 3                                                                             OCH.sub.3                                                                              CH  mp: 86-89° C. (E;                                                       E)                             I.293                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                   I.294                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 83-88° C. (E;                                                       E)                             I.295                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 90-92° C. (E;                                                       E)                             I.296                                                                             (CH.sub.2).sub.3 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  mp: 50-52° C. (E;                                                       E)                             I.297                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                   I.298                                                                             CH.sub.2 C.sub.6 H.sub.5                                                                   2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 41-43° C. (E;                                                       E)                             I.299                                                                             CH.sub.3    3-C(CH.sub.3).sub.3                                                                   5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                   I.300                                                                             CH.sub.3    3-C(CH.sub.3).sub.3                                                                   5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              N   mp: 82-86° C. (E;                                                       E)                             I.301                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              CH  mp: 65-67°  C. (E;                                                      E)                             I.302                                                                             CH.sub.2 CHCH.sub.2                                                                        2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              CH  mp: 83-86° C. (E;                                                       E)                             I.303                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              CH  mp: 92-94° C. (E;                                                       E)                             I.304                                                                             CH(CH.sub.3).sub.2                                                                         2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              N   mp: 96-98° C. (E;                                                       E)                             I.305                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 (CH.sub.2).sub.2 CH.sub.3                                                             OCH.sub.3                                                                              CH  mp: 50-52° C. (E;                                                       E)                             I.306                                                                             CH.sub.3    2-CH.sub.3                                                                            H    4 CH(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                              N   mp: 73-75° C. (E;                                                       E)                             I.307                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                   I.308                                                                             C.sub.2 H.sub.5                                                                            2-CH.sub.3                                                                            H    4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              CH  mp: 52-55° C. (E;                                                       E)                             I.309                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 CH.sub.3                                                                              OCH.sub.3                                                                              CH  resin (E; E)                   I.310                                                                             (CH.sub.2).sub.2 CH.sub.3                                                                  2-CH.sub.3                                                                            5-CH.sub.3                                                                          4 C.sub.2 H.sub.5                                                                       OCH.sub.3                                                                              CH  mp: 85-87°  C. (E;                                                      E)                             __________________________________________________________________________      P* = position of the group CR.sup.4 NOR.sup.1 relative to the OCH.sub.2        bridge                                                                         c-C.sub.3 H.sub.5 = cyclopropyl                                          

Table 1: Compounds of the general formula I.1, in which the combination of the substituents R¹, R², R³, R⁴ and X for a compound corresponds to a line in Table A ##STR6## Table 2: Compounds of the general formula I.2, in which the combination of the substituents R¹, R², R³, R⁴ and X for a compound corresponds to a line in Table B ##STR7## Table 3: Compounds of the general formula I.3, in which the combination of the substituents R¹, R², R³, R⁴ and X for a compound corresponds to a line in Table A ##STR8## Table 4: Compounds of the general formula I.4, in which the combination of the substituents R¹, R², R³, R⁴ and X for a compound corresponds to a line in Table B ##STR9## Table 5: Compounds of the general formula I.5, in which the combination of the substituents R¹, R², R³, R⁴, R⁵, R⁶ and X for a compound corresponds to a line in Table C ##STR10## Table 6: Compounds of the general formula I.2, in which R⁴ is cyclopropyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 7: Compounds of the general formula I.2, in which R⁴ is cyclopentyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 8: Compounds of the general formula I.2, in which R⁴ is cyclohexyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 9: Compounds of the general formula I.2, in which R⁴ is CF₃ and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 10: Compounds of the general formula I.2, in which R⁴ is CH₂ Cl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 11: Compounds of the general formula I.2, in which R⁴ is CH₂ CH₂ C₁ and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 12: Compounds of the general formula I.4, in which R⁴ is cyclopropyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 13: Compounds of the general formula I.4, in which R⁴ is cyclopentyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 14: Compounds of the general formula I.4, in which R⁴ is cyclohexyl and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 15: Compounds of the general formula I.4, in which R⁴ is CF₃ and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 16: Compounds of the general formula I.4, in which R⁴ is CH₂ C₁ and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 17: Compounds of the general formula I.4, in which R⁴ is CH₂ CH₂ C₁ and the combination of the substituents R¹, R², R³ and X for a compound corresponds to a line in Table D

Table 18: Compounds of the general formula I.2, in which R⁴ is cyclopropyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 19: Compounds of the general formula I.2, in which R⁴ is cyclopentyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 20: Compounds of the general formula I.2, in which R⁴ is cyclohexyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 21: Compounds of the general formula I.2, in which R⁴ is CF₃, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 22: Compounds of the general formula I.2, in which R⁴ is CH₂ CH₂ C₁, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 23: Compounds of the general formula I.4, in which R⁴ is cyclopropyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 24: Compounds of the general formula I.4, in which R⁴ is cyclopentyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 25: Compounds of the general formula I.4, in which R⁴ is cyclohexyl, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 26: Compounds of the general formula I.4, in which R⁴ is CF₃, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

Table 27: Compounds of the general formula I.4, in which R⁴ is CH₂ CH₂ C₁, ═X-- is ═N-- and the combination of the substituents R¹, R² and R³ for a compound corresponds to a line in Table E

                                      TABLE A                                      __________________________________________________________________________     Comp. no.                                                                            R.sup.1            R.sup.2                                                                             R.sup.3                                                                           R.sup.4                                                                           X                                          __________________________________________________________________________     A.001 CH.sub.3 --        H    H  H  CH                                         A.002 CH.sub.3 --        H    H  H  N                                          A.003 CH.sub.3 --        2-Cl 5-Cl                                                                              H  CH                                         A.004 CH.sub.3 --        2-Cl 5-Cl                                                                              H  N                                          A.005 CH.sub.3 --        4-Cl H  H  CH                                         A.006 CH.sub.3 --        4-Cl H  H  N                                          A.007 CH.sub.3 --        4-CH.sub.3                                                                          H  H  CH                                         A.008 CH.sub.3 --        4-CH.sub.3                                                                          H  H  N                                          A.009 CH.sub.3 --        5-OCH.sub.3                                                                         H  H  CH                                         A.010 CH.sub.3 --        5-OCH.sub.3                                                                         H  H  N                                          A.011 CH.sub.3 --        6-OCH.sub.3                                                                         H  H  CH                                         A.012 CH.sub.3 --        6-OCH.sub.3                                                                         H  H  N                                          A.013 CH.sub.3 --        H    H  H  CH                                         A.014 CH.sub.3 --CH.sub.2 --                                                                            H    H  H  N                                          A.015 CH.sub.3 --CH.sub.2 --                                                                            2-Cl 5-Cl                                                                              H  CH                                         A.016 CH.sub.3 --CH.sub.2 --                                                                            2-Cl 5-Cl                                                                              H  N                                          A.017 CH.sub.3 --CH.sub.2 --                                                                            4-Cl H  H  CH                                         A.018 CH.sub. 3 --CH.sub.2 --                                                                           4-Cl H  H  N                                          A.019 CH.sub.3 --CH.sub.2 --                                                                            4-CH.sub.3                                                                          H  H  CH                                         A.020 CH.sub.3 --CH.sub.2 --                                                                            4-CH.sub.3                                                                          H  H  N                                          A.021 CH.sub.3 --CH.sub.2 --                                                                            5-OCH.sub.3                                                                         H  H  CH                                         A.022 CH.sub.3 --CH.sub.2 --                                                                            5-OCH.sub.3                                                                         H  H  N                                          A.023 CH.sub.3 --CH.sub.2 --                                                                            6-OCH.sub.3                                                                         H  H  CH                                         A.024 CH.sub.3 --CH.sub.2 --                                                                            6-OCH.sub.3                                                                         H  H  N                                          A.025 CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                                 H    H  H  CH                                         A.026 CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                                 H    H  H  N                                          A.027 CH.sub.2 ═CH--CH.sub.2 --                                                                     H    H  H  CH                                         A.028 CH.sub.2 ═CH--CH.sub.2 --                                                                     H    H  H  N                                          A.029 CH.sub.3 --CH(CH.sub.3)--                                                                         H    H  H  CH                                         A.030 CH.sub.3 --CH(CH.sub.3)--                                                                         H    H  H  N                                          A.031 HC.tbd.C--CH.sub.2 --                                                                             H    H  H  CH                                         A.032 HC.tbd.C--CH.sub.2 --                                                                             H    H  H  N                                          A.033 cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                               H    H  H  CH                                         A.034 cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                               H    H  H  N                                          A.035 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                      H    H  H  CH                                         A.036 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                      H    H  H  N                                          A.037 CH.sub.3 --CH═CH--CH.sub.2 --                                                                 H    H  H  CH                                         A.038 CH.sub.3 --CH═CH--CH.sub.2 --                                                                 H    H  H  N                                          A.039 CH.sub.3 --(CH.sub.2).sub.5 --                                                                    H    H  H  CH                                         A.040 CH.sub.3 --(CH.sub.2).sub.5 --                                                                    H    H  H  N                                          A.041 cyclo-C.sub.6 H.sub.11 --                                                                         H    H  H  CH                                         A.042 cyclo-C.sub.6 H.sub.11 --                                                                         H    H  H  N                                          A.043 C.sub.6 H.sub.5 --CH.sub.2 --                                                                     H    H  H  CH                                         A.044 C.sub.6 H.sub.5 --CH.sub.2 --                                                                     H    H  H  N                                          A.045 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                               H    H  H  CH                                         A.046 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                               H    H  H  N                                          A.047 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub. 2 --                                                       H    H  H  CH                                         A.048 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                                        H    H  H  N                                          A.049 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2 --                                                    H    H  H  CH                                         A.050 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2 --                                                    H    H  H  N                                          A.051 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                               H    H  H  CH                                         A.052 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                               H    H  H  N                                          A.053 C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                             H    H  H  CH                                         A.054 C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                             H    H  H  N                                          A.055 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                               H    H  H  CH                                         A.056 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                               H    H  H  N                                          A.057 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                                          H    H  H  CH                                         A.058 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub. 2 --CH.sub.2 --                                         H    H  H  N                                          A.059 t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                              H    H  H  CH                                         A.060 t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                              H    H  H  N                                          A.061 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                      H    H  H  CH                                         A.062 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                      H    H  H  N                                          A.063 Cl--CH═CH--CH.sub.2 --                                                                        H    H  H  CH                                         A.064 Cl--CH═CH--CH.sub.2 --                                                                        H    H  H  N                                          A.065 C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                                                  H  H  CH                                         A.066 C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                                                  H  H  N                                          A.067 CH.sub.3 --C(CH.sub.3).sub.2 --                                                                   H    H  H  CH                                         A.068 CH.sub.3 --C(CH.sub.3).sub.2 --                                                                   H    H  H  N                                          A.069 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                              H    H  H  CH                                         A.070 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                              H    H  H  N                                          A.071 CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                               H    H  H  CH                                         A.072 CH.sub.2 ═C(CH.sub.3)-- CH.sub.2                                                              H    H  H  N                                          A.073 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                                   H    H  H  CH                                         A.074 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                                   H    H  H  N                                          A.075 CH.sub.3 --(CH.sub.2).sub.4 --                                                                    H    H  H  CH                                         A.076 CH.sub.3 --(CH.sub.2).sub.4 --                                                                    H    H  H  N                                          A.077 2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  H  CH                                         A.078 2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  H  N                                          A.079 3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  H  CH                                         A.080 3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  H  N                                          A.081 2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                               H    H  H  CH                                         A.082 2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                               H    H  H  N                                          A.083 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                      H    H  H  CH                                         A.084 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                      H    H  H  N                                          A.085 2,6-Cl.sub.2 -- C.sub.6 H.sub.3 --CH.sub.2 --                                                     H    H  H  CH                                         A.086 2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                      H    H  H  N                                          A.087 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                          H    H  H  CH                                         A.088 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                          H    H  H  N                                          A.089 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                               H    H  H  CH                                         A.090 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                               H    H  H  N                                          A.091 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2 --                                         H    H  H  CH                                         A.092 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2 --                                         H    H  H  N                                          A.093 4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                                     H-   H  H  CH                                         A.094 4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                                     H-   H  H  N                                          A.095 CH.sub.3           H    H  CH.sub.3                                                                          CH                                         A.096 CH.sub.3           H    H  CH.sub. 3                                                                         N                                          A.097 CH.sub.3           2-Cl 5-Cl                                                                              CH.sub.3                                                                          CH                                         A.098 CH.sub.3           2-Cl 5-Cl                                                                              CH.sub.3                                                                          N                                          A.099 CH.sub.3           4-Cl H  CH.sub.3                                                                          CH                                         A.100 CH.sub.3           4-Cl H  CH.sub.3                                                                          N                                          A.101 CH.sub.3           4-CH.sub.3                                                                          H  CH.sub.3                                                                          CH                                         A.102 CH.sub.3           4-CH.sub.3                                                                          H  CH.sub.3                                                                          N                                          A.103 CH.sub.3           5-OCH.sub.3                                                                         H  CH.sub.3                                                                          CH                                         A.104 CH.sub.3           5-OCH.sub.3                                                                         H  CH.sub.3                                                                          N                                          A.105 CH.sub.3           6-OCH.sub.3                                                                         H  CH.sub.3                                                                          CH                                         A.106 CH.sub.3           6-OCH.sub.3                                                                         H  CH.sub.3                                                                          N                                          A.107 CH.sub.3 --CH.sub.2                                                                               H    H  CH.sub.3                                                                          CH                                         A.108 CH.sub.3 --CH.sub.2                                                                               H    H  CH.sub.3                                                                          N                                          A.109 CH.sub.3 --CH.sub.2                                                                               2-Cl 5-Cl                                                                              CH.sub.3                                                                          CH                                         A.110 CH.sub.3 --CH.sub.2                                                                               2-Cl 5-Cl                                                                              CH.sub.3                                                                          N                                          A.111 CH.sub.3 --CH.sub.2                                                                               4-Cl H  CH.sub.3                                                                          CH                                         A.112 CH.sub.3 --CH.sub.2                                                                               4-Cl H  CH.sub.3                                                                          N                                          A.113 CH.sub.3 --CH.sub.2                                                                               4-CH.sub.3                                                                          H  CH.sub.3                                                                          CH                                         A.114 CH.sub.3 --CH.sub.2                                                                               4-CH.sub.3                                                                          H  CH.sub.3                                                                          N                                          A.115 CH.sub.3 --CH.sub.2                                                                               5-OCH.sub.3                                                                         H  CH.sub.3                                                                          CH                                         A.116 CH.sub.3 --CH.sub.2                                                                               5-OCH.sub.3                                                                         H  CH.sub. 3                                                                         N                                          A.117 CH.sub.3 --CH.sub.2                                                                               6-OCH.sub.3                                                                         H  CH.sub.3                                                                          CH                                         A.118 CH.sub.3 --CH.sub.2                                                                               6-OCH.sub.3                                                                         H  CH.sub.3                                                                          N                                          A.119 CH.sub.3 --CH.sub.2 --CH.sub.2                                                                    H    H  CH.sub.3                                                                          CH                                         A.120 CH.sub.3 --CH.sub.2 --CH.sub.2                                                                    H    H  CH.sub.3                                                                          N                                          A.121 CH.sub.2 ═CH--CH.sub.2                                                                        H    H  CH.sub.3                                                                          CH                                         A.122 CH.sub.2 ═CH--CH.sub.2                                                                        H    H  CH.sub.3                                                                          N                                          A.123 CH.sub.3 --CH(CH.sub.3)                                                                           H    H  CH.sub.3                                                                          CH                                         A.124 CH.sub.3 --CH(CH.sub.3)                                                                           H    H  CH.sub.3                                                                          N                                          A.125 HC.tbd.C--CH.sub.2 H    H  CH.sub.3                                                                          CH                                         A.126 HC.tbd.C--CH.sub.2 H    H  CH.sub.3                                                                          N                                          A.127 cyclo-C.sub.3 H.sub.5 --CH.sub.2                                                                  H    H  CH.sub.3                                                                          CH                                         A.128 cyclo-C.sub.3 H.sub.5 --CH.sub.2                                                                  H    H  CH.sub.3                                                                          N                                          A.129 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                                                         H    H  CH.sub.3                                                                          CH                                         A.130 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                                                         H    H  CH.sub.3                                                                          N                                          A.131 CH.sub.3 --CH═CH--CH.sub.2                                                                    H    H  CH.sub.3                                                                          CH                                         A.132 CH.sub.3 --CH═ CH--CH.sub.2                                                                   H    H  CH.sub.3                                                                          N                                          A.133 CH.sub.3 --(CH.sub.2).sub.5                                                                       H    H  CH.sub.3                                                                          CH                                         A.134 CH.sub.3 --(CH.sub.2).sub.5                                                                       H    H  CH.sub.3                                                                          N                                          A.135 cyclo-C.sub.6 H.sub.11                                                                            H    H  CH.sub.3                                                                          CH                                         A.136 cyclo-C.sub.6 H.sub.11                                                                            H    H  CH.sub.3                                                                          N                                          A.137 C.sub.6 H.sub.5 --CH.sub.2                                                                        H    H  CH.sub.3                                                                          CH                                         A.138 C.sub.6 H.sub.5 --CH.sub.2                                                                        H    H  CH.sub.3                                                                          N                                          A.139 4-Cl-C.sub.6 H.sub.4 --CH.sub.2                                                                   H    H  CH.sub.3                                                                          CH                                         A.140 4-Cl-C.sub.6 H.sub.4 --CH.sub.2                                                                   H    H  CH.sub.3                                                                          N                                          A.141 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                                                           H    H  CH.sub.3                                                                          CH                                         A.142 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                                                           H    H  CH.sub.3                                                                          N                                          A.143 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                                                       H    H  CH.sub.3                                                                          CH                                         A.144 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                                                       H    H  CH.sub.3                                                                          N                                          A.145 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                                                  H    H  CH.sub.3                                                                          CH                                         A.146 C.sub.6 H.sub.5 --CH.sub.2 -- CH.sub.2 --CH.sub.2                                                 H    H  CH.sub.3                                                                          N                                          A.147 C.sub.6 H.sub.5 --(CH.sub.2).sub.4                                                                H    H  CH.sub.3                                                                          CH                                         A.148 C.sub.6 H.sub.5 --(CH.sub.2).sub.4                                                                H    H  CH.sub.3                                                                          N                                          A.149 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                                  H    H  CH.sub.3                                                                          CH                                         A.150 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                                  H    H  CH.sub.3                                                                          N                                          A.151 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2                                             H    H  CH.sub.3                                                                          CH                                         A.152 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2                                             H    H  CH.sub.3                                                                          N                                          A.153 t-C.sub.4 H.sub.9 O--CO--CH.sub.2                                                                 H    H  CH.sub.3                                                                          CH                                         A.154 t-C.sub.4 H.sub.9 O--CO--CH.sub.2                                                                 H    H  CH.sub.3                                                                          N                                          A.155 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3                                                         H    H  CH.sub.3                                                                          CH                                         A.156 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3                                                         H    H  CH.sub.3                                                                          N                                          A.157 Cl--CH═CH--CH.sub.2                                                                           H    H  CH.sub.3                                                                          CH                                         A.158 Cl--CH═CH--CH.sub.2                                                                           H    H  CH.sub.3                                                                          N                                          A.159 C.sub.2 H.sub. 5   6-OC.sub.2 H.sub.5                                                                  H  CH.sub.3                                                                          CH                                         A.160 C.sub.2 H.sub.5    6-OC.sub.2 H.sub.5                                                                  H  CH.sub.3                                                                          N                                          A.161 CH.sub.3 --C(CH.sub.2).sub.2                                                                      H    H  CH.sub.3                                                                          CH                                         A.162 CH.sub.3 --C(CH.sub.2).sub.2                                                                      H    H  CH.sub.3                                                                          N                                          A.163 CH.sub.3 --CH(CH.sub.3)--CH.sub.2                                                                 H    H  CH.sub.3                                                                          CH                                         A.164 CH.sub.3 --CH(CH.sub.3)--CH.sub.2                                                                 H    H  CH.sub.3                                                                          N                                          A.165 CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                               H    H  CH.sub.3                                                                          CH                                         A.166 CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                               H    H  CH.sub.3                                                                          N                                          A.167 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2                                                      H    H  CH.sub.3                                                                          CH                                         A.168 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2                                                      H    H  CH.sub.3                                                                          N                                          A.169 CH.sub.3 --(CH.sub.2).sub.4                                                                       H    H  CH.sub.3                                                                          CH                                         A.170 CH.sub.3 --(CH.sub.2).sub.4                                                                       H    H  CH.sub.3                                                                          N                                          A.171 2-F--C.sub.6 H.sub.4 --CH.sub.2                                                                   H    H  CH.sub.3                                                                          CH                                         A.172 2-F--C.sub.6 H.sub.4 --CH.sub.2                                                                   H    H  CH.sub.3                                                                          N                                          A.173 3-F--C.sub.6 H.sub.4 --CH.sub. 2                                                                  H    H  CH.sub.3                                                                          CH                                         A.174 3-F--C.sub.6 H.sub.4 --CH.sub.2                                                                   H    H  CH.sub.3                                                                          N                                          A.175 2-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                                  H    H  CH.sub.3                                                                          CH                                         A.176 2-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                                  H    H  CH.sub.3                                                                          N                                          A.177 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                         H    H  CH.sub.3                                                                          CH                                         A.178 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                         H    H  CH.sub.3                                                                          N                                          A.179 2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                         H    H  CH.sub.3                                                                          CH                                         A.180 2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                         H    H  CH.sub.3                                                                          N                                          A.181 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                                                             H    H  CH.sub.3                                                                          CH                                         A.182 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                                                             H    H  CH.sub.3                                                                          N                                          A.183 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                                                  H    H  CH.sub.3                                                                          CH                                         A.184 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                                                  H    H  CH.sub.3                                                                          N                                          A.185 4-Cl-C.sub.6 H.sub.4 --CH.sub.2 CH═CH--CH.sub.2                                               H    H  CH.sub.3                                                                          CH                                         A.186 4-Cl-C.sub.6 H.sub.4 --CH.sub.2 CH═CH--CH.sub.2                                               H    H  CH.sub.3                                                                          N                                          A.187 4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                                     H    H  CH.sub.3                                                                          CH                                         A.188 4-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --CH═CH--CH.sub.2                                     H    H  CH.sub.3                                                                          N                                          A.189 CH.sub.3           H    H  C.sub.6 H.sub.5                                                                   CH                                         A.190 CH.sub.3           H    H  C.sub.6 H.sub.5                                                                   N                                          A.191 C.sub.2 H.sub.5    H    H  C.sub.6 H.sub.5                                                                   CH                                         A.192 C.sub.2 H.sub.5    H    H  C.sub.6 H.sub.5                                                                   N                                          A.193 CH.sub.3 --CH.sub.2 --CH.sub.2                                                                    H    H  C.sub.6 H.sub.5                                                                   CH                                         A.194 CH.sub.3 --CH.sub.2 --CH.sub.2                                                                    H    H  C.sub.6 H.sub.5                                                                   N                                          A.195 CH.sub.3 --(CH.sub.2).sub.5                                                                       H    H  C.sub.6 H.sub.5                                                                   CH                                         A.196 CH.sub.3 --(CH.sub.2).sub.5                                                                       H    H  C.sub.6 H.sub.5                                                                   N                                          A.197 C.sub.6 H.sub.5 --CH.sub.2                                                                        H    H  C.sub.6 H.sub.5                                                                   CH                                         A.198 C.sub.6 H.sub.5 --CH.sub.2                                                                        H    H  C.sub.6 H.sub.5                                                                   N                                          __________________________________________________________________________

                                      TABLE B                                      __________________________________________________________________________     Comp.                                                                          no. R.sup.1       R.sup.2  R.sup.3                                                                               R.sup.4  X                                   __________________________________________________________________________     B.001                                                                              CH.sub.3 --   H        H      H        CH                                  B.002                                                                              CH.sub.3 --   H        H      H        N                                   B.003                                                                              CH.sub.3 --   2-Cl     H      H        CH                                  B.004                                                                              CH.sub.3 --   2-Cl     H      H        N                                   B.005                                                                              CH.sub.3 --   2-CH.sub.3                                                                              H      H        CH                                  B.006                                                                              CH.sub.3 --   2-CH.sub.3                                                                              H      H        N                                   B.007                                                                              CH.sub.3 --   2-OCH.sub.3                                                                             H      H        CH                                  B.008                                                                              CH.sub.3 --   2-OCH.sub.3                                                                             H      H        N                                   B.009                                                                              CH.sub.3 --   3-Cl     H      H        CH                                  B.010                                                                              CH.sub.3 --   3-Cl     H      H        N                                   B.011                                                                              CH.sub.3 --   3-CH.sub.3                                                                              H      H        CH                                  B.012                                                                              CH.sub.3 --   3-CH.sub.3                                                                              H      H        N                                   B.013                                                                              CH.sub.3 --   3-OCH.sub.3                                                                             H      H        CH                                  B.014                                                                              CH.sub.3 --   3-OCH.sub.3                                                                             H      H        N                                   B.015                                                                              CH.sub.3      2-Cl     6-Cl   H        CH                                  B.016                                                                              CH.sub.3      2-Cl     6-Cl   H        N                                   B.017                                                                              CH.sub.3 --CH.sub.2 --                                                                       H        H      H        CH                                  B.018                                                                              CH.sub.3 --CH.sub.2 --                                                                       H        H      H        N                                   B.019                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     H      H        CH                                  B.020                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     H      H        N                                   B.021                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-CH.sub.3                                                                              H      H        CH                                  B.022                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-CH.sub.3                                                                              H      H        N                                   B.023                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-OCH.sub.3                                                                             H      H        CH                                  B.024                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-OCH.sub.3                                                                             H      H        N                                   B.025                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-Cl     H      H        CH                                  B.026                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-Cl     H      H        N                                   B.027                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-CH.sub.3                                                                              H      H        CH                                  B.028                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-CH.sub.3                                                                              H      H        N                                   B.029                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-OCH.sub.3                                                                             H      H        CH                                  B.030                                                                              CH.sub.3 --CH.sub.2 --                                                                       3-OCH.sub.3                                                                             H      H        N                                   B.031                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     H      H        CH                                  B.032                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     6-Cl   H        N                                   B.033                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            H        6-Cl   H        CH                                  B.034                                                                              CH.sub.3 --CH.sub. 2 --CH.sub.2 --                                                           H        H      H        N                                   B.035                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                H        H      H        CH                                  B.036                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                H        H      H        N                                   B.037                                                                              CH.sub.3 --CH(CH.sub.3)--                                                                    H        H      H        CH                                  B.038                                                                              CH.sub.3 --CH(CH.sub.3)--                                                                    H        H      H        N                                   B.039                                                                              HC.tbd.C--CH.sub.2 --                                                                        H        H      H        CH                                  B.040                                                                              HC.tbd.C--CH.sub.2 --                                                                        H        H      H        N                                   B.041                                                                              cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                          H        H      H        CH                                  B.042                                                                              cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                          H        H      H        N                                   B.043                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                 H        H      H        CH                                  B.044                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                 H        H      H        N                                   B.045                                                                              CH.sub.3 --CH═CH--CH.sub.2 --                                                            H        H      H        CH                                  B.046                                                                              CH.sub.3 --CH═CH--CH.sub.2 --                                                            H        H      H        N                                   B.047                                                                              CH.sub.3 --(CH.sub.2).sub.5 --                                                               H        H      H        CH                                  B.048                                                                              CH.sub.3 --(CH.sub.2).sub.5 --                                                               H        H      H        N                                   B.049                                                                              cyclo-C.sub.6 H.sub.11 --                                                                    H        H      H        CH                                  B.050                                                                              cyclo-C.sub.6 H.sub.11 --                                                                    H        H      H        N                                   B.051                                                                              C.sub.6 H.sub.5 --CH.sub.2 --                                                                H        H      H        CH                                  B.052                                                                              C.sub.6 H.sub.5 --CH.sub.2 --                                                                H        H      H        N                                   B.053                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        CH                                  B.054                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        N                                   B.055                                                                              3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                                   H        H      H        CH                                  B.056                                                                              3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                                   H        H      H        N                                   B.057                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        CH                                  B.058                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        N                                   B.059                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                          H        H      H        CH                                  B.060                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                          H        H      H        N                                   B.061                                                                              C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                        H        H      H        CH                                  B.062                                                                              C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                        H        H      H        N                                   B.063                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                             H        H      H        CH                                  B.064                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                             H        H      H        N                                   B.065                                                                              4-F--C.sub.6 H.sub.4 --                                                                      H        H      H        CH                                      CH═CHCH.sub.2 CH.sub.2                                                 B.066                                                                              4-F--C.sub.6 H.sub.4 --                                                                      H        H      H        N                                       CH═CHCH.sub.2 CH.sub.2                                                 B.067                                                                              t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                         H        H      H        CH                                  B.068                                                                              t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                         H        H      H        N                                   B.069                                                                              t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                 H        H      H        CH                                  B.070                                                                              t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                 H        H      H        N                                   B.071                                                                              Cl--CH═CH--CH.sub.2 --                                                                   H        H      H        CH                                  B.072                                                                              Cl--CH═CH--CH.sub.2 --                                                                   H        H      H        N                                   B.073                                                                              C.sub.2 H.sub.5                                                                              6-OC.sub.2 H.sub.5                                                                      H      H        CH                                  B.074                                                                              C.sub.2 H.sub.5                                                                              6-OC.sub.2 H.sub.5                                                                      H      H        N                                   B.075                                                                              CH.sub.3 --C(CH.sub.3).sub.2 --                                                              H        H      H        CH                                  B.076                                                                              CH.sub.3 --C(CH.sub.3).sub.2 --                                                              H        H      H        N                                   B.077                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                         H        H      H        CH                                  B.078                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                         H        H      H        N                                   B.079                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                                                       H        H      H        CH                                  B.080                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                                                       H        H      H        N                                   B.081                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   H        H      H        CH                                  B.082                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   H        H      H        N                                   B.083                                                                              CH.sub.3 --(CH.sub.2).sub.4 --                                                               H        H      H        CH                                  B.084                                                                              CH.sub.3 --(CH.sub.2).sub.4 --                                                               H        H      H        N                                   B.085                                                                              2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                           H        H      H        CH                                  B.086                                                                              2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                           H        H      H        N                                   B.087                                                                              3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                           H        H      H        CH                                  B.088                                                                              3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                           H        H      H        N                                   B.089                                                                              2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        CH                                  B.090                                                                              2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                          H        H      H        N                                   B.091                                                                              3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                 H        H      H        CH                                  B.092                                                                              3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                 H        H      H        N                                   B.093                                                                              2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                 H        H      H        CH                                  B.094                                                                              2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                 H        H      H        N                                   B.095                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                     H        H      H        CH                                  B.096                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                     H        H      H        N                                   B.097                                                                              C.sub.6 H.sub.5 --CH═CH--                                                                H        H      H        CH                                      CH.sub.2 --CH.sub.2 --                                                     B.098                                                                              C.sub.6 H.sub.5 --CH═CH--                                                                H        H      H        N                                       CH.sub.2 --CH.sub.2 --                                                     B.099                                                                              4-Cl--C.sub.6 H.sub.4 --                                                                     H        H      H        CH                                      CH.sub.2 CH═CHCH.sub.2                                                 B.100                                                                              4-Cl-- C.sub.6 H.sub.4 --                                                                    H        H      H        N                                       CH.sub.2 CH═CHCH.sub.2                                                 B.101                                                                              4-CF.sub.3 --C.sub.6 H.sub.4 --                                                              H        H      H        CH                                      CH.sub.2 CH═CHCH.sub.2                                                 B.102                                                                              4-CF.sub.3 --C.sub.6 H.sub.4 --                                                              H        H      H        N                                       CH.sub.2 CH═CHCH.sub.2                                                 B.103                                                                              CH.sub.3      H        H      CH.sub.3 CH                                  B.104                                                                              CH.sub.3      H        H      CH.sub.3 N                                   B.105                                                                              CH.sub.3      2-Cl     H      CH.sub.3 CH                                  B.106                                                                              CH.sub.3      2-Cl     H      CH.sub.3 N                                   B.107                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.108                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.109                                                                              CH.sub.3      2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.110                                                                              CH.sub.3      2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.111                                                                              CH.sub.3      3-Cl     H      CH.sub.3 CH                                  B.112                                                                              CH.sub.3      3-Cl     H      CH.sub.3 N                                   B.113                                                                              CH.sub.3      3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.114                                                                              CH.sub.3      3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.115                                                                              CH.sub.3      3-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.116                                                                              CH.sub.3      3-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.117                                                                              CH.sub.3      2-Cl     6-Cl   CH.sub.3 CH                                  B.118                                                                              CH.sub.3      2-Cl     6-Cl   CH.sub.3 N                                   B.119                                                                              CH.sub.3 --CH.sub.2                                                                          H        H      CH.sub.3 CH                                  B.120                                                                              CH.sub.3 --CH.sub.2                                                                          H        H      CH.sub.3 N                                   B.121                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     H      CH.sub.3 CH                                  B.122                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     H      CH.sub.3 N                                   B.123                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.124                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.125                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.126                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.127                                                                              CH.sub.3 --CH.sub.2                                                                          3-Cl     H      CH.sub.3 CH                                  B.128                                                                              CH.sub.3 --CH.sub.2                                                                          3-Cl     H      CH.sub.3 N                                   B.129                                                                              CH.sub.3 --CH.sub.2                                                                          3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.130                                                                              CH.sub.3 --CH.sub.2                                                                          3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.131                                                                              CH.sub.3 --CH.sub.2                                                                          3-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.132                                                                              CH.sub.3 --CH.sub.2                                                                          3-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.133                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     6-Cl   CH.sub.3 CH                                  B.134                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     6-Cl   CH.sub.3 N                                   B.135                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               H        H      CH.sub.3 CH                                  B.136                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               H        H      CH.sub.3 N                                   B.137                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   H        H      CH.sub.3 CH                                  B.138                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   H        H      CH.sub.3 N                                   B.139                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      H        H      CH.sub.3 CH                                  B.140                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      H        H      CH.sub.3 N                                   B.141                                                                              HC.tbd.C--CH.sub.2                                                                           H        H      CH.sub.3 CH                                  B.142                                                                              HC.tbd.C--CH.sub.2                                                                           H        H      CH.sub.3 N                                   B.143                                                                              cyclo-C.sub.3 H.sub.5 --CH.sub.2                                                             H        H      CH.sub.3 CH                                  B.144                                                                              cyclo-C.sub.3 H.sub.5 --CH.sub.2                                                             H        H      CH.sub.3 N                                   B.145                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                                                    H        H      CH.sub.3 CH                                  B.146                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2                                                    H        H      CH.sub.3 N                                   B.147                                                                              CH.sub.3 --CH═CH--CH.sub.2                                                               H        H      CH.sub.3 CH                                  B.148                                                                              CH.sub.3 --CH═CH--CH.sub.2                                                               H        H      CH.sub.3 N                                   B.149                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  H        H      CH.sub.3 CH                                  B.150                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  H        H      CH.sub.3 N                                   B.151                                                                              cyclo-C.sub.6 H.sub.11                                                                       H        H      CH.sub.3 CH                                  B.152                                                                              cyclo-C.sub.6 H.sub.11                                                                       H        H      CH.sub.3 N                                   B.153                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   H        H      CH.sub.3 CH                                  B.154                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   H        H      CH.sub.3 N                                   B.155                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                             H        H      CH.sub.3 CH                                  B.156                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                             H        H      CH.sub.3 N                                   B.157                                                                              3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                                                      H        H      CH.sub.3 CH                                  B.158                                                                              3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2                                                      H        H      CH.sub.3 N                                   B.159                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                                                  H        H      CH.sub.3 CH                                  B.160                                                                              4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --CH.sub.2                                                  H        H      CH.sub.3 N                                   B.161                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                                             H        H      CH.sub.3 CH                                  B.162                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2                                             H        H      CH.sub.3 N                                   B.163                                                                              C.sub.6 H.sub.5 --(CH.sub.2).sub.4                                                           H        H      CH.sub.3 CH                                  B.164                                                                              C.sub.6 H.sub.5 --(CH.sub.2).sub.4                                                           H        H      CH.sub.3 N                                   B.165                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                             H        H      CH.sub.3 CH                                  B.166                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                             H        H      CH.sub.3 N                                   B.167                                                                              4-F--C.sub.6 H.sub.4 --CH═--CHCH.sub.2                                                   H        H      CH.sub.3 CH                                  B.168                                                                              4-F--C.sub.6 H.sub.4 --CH═--CHCH.sub.2                                                   H        H      CH.sub.3 N                                   B.169                                                                              t-C.sub.4 --H.sub.9 O--CO--CH.sub.2                                                          H        H      CH.sub.3 CH                                  B.170                                                                              t-C.sub.4 --H.sub.9 O--CO--CH.sub.2                                                          H        H      CH.sub.3 N                                   B.171                                                                              t-C.sub.4 --H.sub.9 O--CO--(CH.sub.2).sub.3                                                  H        H      CH.sub.3 CH                                  B.172                                                                              t-C.sub.4 --H.sub.9 O--CO--(CH.sub.2).sub.3                                                  H        H      CH.sub.3 N                                   B.173                                                                              Cl--CH═CH--CH.sub.2                                                                      H        H      CH.sub.3 CH                                  B.174                                                                              Cl--CH═CH--CH.sub.2                                                                      H        H      CH.sub.3 N                                   B.175                                                                              C.sub.2 H.sub.5                                                                              6-OC.sub.2 H.sub.5                                                                      H      CH.sub.3 CH                                  B.176                                                                              C.sub.2 H.sub.5                                                                              6-OC.sub.2 H.sub.5                                                                      H      CH.sub.3 N                                   B.177                                                                              CH.sub.3 --C(CH.sub.3).sub.2                                                                 H        H      CH.sub.3 CH                                  B.178                                                                              CH.sub.3 --C(CH.sub.3).sub.2                                                                 H        H      CH.sub.3 N                                   B.179                                                                              CH.sub. 3 --CH(CH.sub.3)--CH.sub.2                                                           H        H      CH.sub.3 CH                                  B.180                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2                                                            H        H      CH.sub.3 N                                   B.181                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                          H        H      CH.sub.3 CH                                  B.182                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                          H        H      CH.sub.3 N                                   B.183                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   H        H      CH.sub.3 CH                                  B.184                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   H        H      CH.sub.3 N                                   B.185                                                                              CH.sub.3 --(CH.sub.2).sub.4                                                                  H        H      CH.sub.3 CH                                  B.186                                                                              CH.sub.3 --(CH.sub.2).sub.4                                                                  H        H      CH.sub.3 N                                   B.187                                                                              2-F--C.sub.6 H.sub.4 --CH.sub.2                                                              H        H      CH.sub.3 CH                                  B.188                                                                              2-F--C.sub.6 H.sub.4 --CH.sub.2                                                              H        H      CH.sub.3 N                                   B.189                                                                              3-F--C.sub.6 H.sub.4 --CH.sub.2                                                              H        H      CH.sub.3 CH                                  B.190                                                                              3-F--C.sub.6 H.sub.4 --CH.sub.2                                                              H        H      CH.sub.3 N                                   B.191                                                                              2-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                             H        H      CH.sub.3 CH                                  B.192                                                                              2-Cl--C.sub.6 H.sub.4 --CH.sub.2                                                             H        H      CH.sub.3 N                                   B.193                                                                              3,4-Cl.sub.2 -- C.sub.6 H.sub.3 --CH.sub.2                                                   H        H      CH.sub.3 CH                                  B.194                                                                              3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                    H        H      CH.sub.3 N                                   B.195                                                                              2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                    H        H      CH.sub.3 CH                                  B.196                                                                              2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2                                                    H        H      CH.sub.3 N                                   B.197                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                                                        H        H      CH.sub.3 CH                                  B.198                                                                              C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2                                                        H        H      CH.sub.3 N                                   B.199                                                                              C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                                             H        H      CH.sub.3 CH                                  B.200                                                                              C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2                                             H        H      CH.sub.3 N                                   B.201                                                                              4-Cl--C.sub.6 H.sub.4 --                                                                     H        H      CH.sub.3 CH                                      CH.sub.2 --CH═CH--CH.sub.2                                             B.202                                                                              4-Cl--C.sub.6 H.sub.4 --                                                                     H        H      CH.sub.3 N                                       CH.sub.2 --CH═CH--CH.sub.2                                             B.203                                                                              4-CF.sub.3 --C.sub.6 H.sub.4 --                                                              H        H      CH.sub.3 CH                                      CH.sub.2 --CH═CH--CH.sub.2                                             B.204                                                                              4-CF.sub.3 --C.sub.6 H.sub. 4 --                                                             H        H      CH.sub.3 N                                       CH.sub.2 --CH═CH--CH.sub.2                                             B.205                                                                              CH.sub.3      H        H      C.sub.6 H.sub.5                                                                         CH                                  B.206                                                                              CH.sub.3      H        H      CH.sub.3 N                                   B.207                                                                              C.sub.2 H.sub.5                                                                              H        H      CH.sub.3 CH                                  B.208                                                                              C.sub.2 H.sub.5                                                                              H        H      CH.sub.3 N                                   B.209                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               H        H      CH.sub.3 CH                                  B.210                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               H        H      CH.sub.3 N                                   B.211                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  H        H      CH.sub.3 CH                                  B.212                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  H        H      CH.sub.3 N                                   B.213                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   H        H      CH.sub.3 CH                                  B.214                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   H        H      CH.sub.3 N                                   B.215                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.216                                                                              CH.sub.3      2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         N                                   B.217                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.218                                                                              C.sub.2 H.sub.5                                                                              2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.219                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.220                                                                              CH.sub.3 --CH.sub.2 --CH.sub. 2                                                              2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.221                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.222                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.223                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.224                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2                                                            2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.225                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2                                                            2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.226                                                                              CH.sub.3 --(CH.sub.2).sub.3                                                                  2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.227                                                                              CH.sub.3 --(CH.sub.2).sub.3                                                                  2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.228                                                                              CH.sub.3 --C(CH.sub.3).sub.2                                                                 2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.229                                                                              CH.sub.3 --C(CH.sub.3).sub.2                                                                 2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.230                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                          2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.231                                                                              CH.sub.2 ═C(CH.sub.3)--CH.sub.2                                                          2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.232                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.233                                                                              CH.sub.3 --CH(CH.sub.3)--CH.sub.2 CH.sub.2                                                   2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.234                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.235                                                                              CH.sub.3 --(CH.sub.2).sub.5                                                                  2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.236                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.237                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.238                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.239                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.240                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.241                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.242                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.243                                                                              CH.sub.3 --(CH.sub.2).sub.3                                                                  2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.244                                                                              CH.sub.3 --(CH.sub.2).sub.3                                                                  2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.245                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.246                                                                              C.sub.6 H.sub.5 --CH.sub.2                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.247                                                                              CH.sub.3      3-CH.sub.3 C(CH.sub.3).sub.2                                                            H      CH.sub.3 CH                                  B.248                                                                              CH.sub.3      3-CH.sub.3 C(CH.sub.3).sub. 2                                                           H      CH.sub.3 N                                   B.249                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     CH                                  B.250                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     N                                   B.251                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     CH                                  B.252                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     N                                   B.253                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     CH                                  B.254                                                                              CH.sub.3 --CH(CH.sub.3)                                                                      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     N                                   B.255                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     CH                                  B.256                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2                                                                     N                                   B.257                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --CH.sub.2                                                          CH                                  B.258                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH(CH.sub.3)                                                                 N                                   B.259                                                                              C.sub.2 H.sub.5                                                                              2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.260                                                                              C.sub.2 H.sub.5                                                                              2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         CH                                  B.261                                                                              C.sub.2 H.sub.5                                                                              2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         N                                   B.262                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.263                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.264                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         CH                                  B.265                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         N                                   B.266                                                                              CH.sub.3      2-Cl     H      CH.sub.3 CH                                  B.267                                                                              CH.sub.3      2-Cl     H      CH.sub.3 N                                   B.268                                                                              C.sub.2 H.sub.5                                                                              2-Cl     H      CH.sub.3 CH                                  B.269                                                                              C.sub.2 H.sub.5                                                                              2-Cl     H      CH.sub.3 N                                   B.270                                                                              CH.sub.3      2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.271                                                                              CH.sub.3      2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.272                                                                              C.sub.2 H.sub.5                                                                              2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.273                                                                              C.sub.2 H.sub.5                                                                              2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.274                                                                              CH.sub.3      2-Cl     5-Cl   CH.sub.3 CH                                  B.275                                                                              CH.sub.3      2-Cl     5-Cl   CH.sub.3 N                                   B.276                                                                              C.sub.2 H.sub.5                                                                              2-Cl     5-Cl   CH.sub.3 CH                                  B.277                                                                              C.sub.2 H.sub.5                                                                              2-Cl     5-Cl   CH.sub.3 N                                   B.278                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2                                                            2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.279                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2                                                            2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         N                                   B.280                                                                              CH.sub.3 --(CH.sub. 2).sub.3                                                                 2-CH.sub.3                                                                              H      C.sub.2 H.sub.5                                                                         N                                   B.281                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2                                                            2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.282                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.283                                                                              C.sub.2 H.sub.5                                                                              2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.284                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.285                                                                              CH.sub.2 ═CH--CH.sub.2                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.286                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2                                                            2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.287                                                                              CH.sub.3 --(CH.sub.2).sub.3                                                                  2-CH.sub.3                                                                              5-CH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                   B.288                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-Cl     H      CH.sub.3 N                                   B.289                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-Cl     H      CH.sub.3 CH                                  B.290                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     H      CH.sub.3 N                                   B.291                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     H      CH.sub.3 CH                                  B.292                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     H      CH.sub.3 N                                   B.293                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     H      CH.sub.3 CH                                  B.294                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.295                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.296                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.297                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.298                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.299                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.300                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.301                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.302                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.303                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.304                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.305                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                3-CH.sub. 3                                                                             H      CH.sub.3 CH                                  B.306                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --CH.sub.2                                                          N                                   B.307                                                                              CH.sub.3      2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --CH.sub.2                                                          CH                                  B.308                                                                              CH.sub.3 --(CH.sub.2).sub.5 --                                                               2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.309                                                                              CH.sub.3 --(CH.sub.2).sub.5 --                                                               2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.310                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.311                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.312                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.313                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.314                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.315                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.316                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.317                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.318                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.319                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.320                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.321                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.322                                                                              N.tbd.C--CH.sub.2 --                                                                         2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.323                                                                              N.tbd.C--CH.sub.2 --                                                                         2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.324                                                                              N.tbd.C--CH.sub.2 --                                                                         2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 N                                   B.325                                                                              N.tbd.C--CH.sub.2 --                                                                         2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 CH                                  B.326                                                                              CH.sub.3      2-CH.sub.3                                                                              H      C.sub.6 H.sub.5                                                                         N                                   B.327                                                                              CH.sub.3      2-CH.sub.3                                                                              H      C.sub.6 H.sub.5                                                                         CH                                  B.328                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-CH.sub.3                                                                              H      C.sub.6 H.sub.5                                                                         N                                   B.329                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-CH.sub.3                                                                              H      C.sub.6 H.sub.5                                                                         CH                                  B.330                                                                              (CH.sub.3).sub.3 COCO--CH.sub.2 --                                                           2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.331                                                                              (CH.sub.3).sub.3 COCO--CH.sub.2 --                                                           2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.332                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.3                                                      2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.333                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.3                                                      2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.334                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.4                                                      2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.335                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.4                                                      2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.336                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.5                                                      2-CH.sub.3                                                                              H      CH.sub.3 N                                   B.337                                                                              (CH.sub.3).sub.3 COCO--(CH.sub.2).sub.5                                                      2-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.338                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.339                                                                              CH.tbd.C--CH.sub.2 --                                                                        2-CH.sub.3                                                                              5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.340                                                                              CH.sub.3      2-F      H      CH.sub.3 N                                   B.341                                                                              CH.sub.3      2-F      H      CH.sub.3 CH                                  B.342                                                                              CH.sub.3 --CH.sub.2                                                                          2-F      H      CH.sub.3 N                                   B.343                                                                              CH.sub.3 --CH.sub.2                                                                          2-F      H      CH.sub.3 CH                                  B.344                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-F      H      CH.sub.3 N                                   B.345                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                            2-F      H      CH.sub.3 CH                                  B.346                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-F      H      CH.sub.3 N                                   B.347                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-F      H      CH.sub.3 CH                                  B.348                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-F      H      CH.sub.3 N                                   B.349                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-F      H      CH.sub.3 CH                                  B.350                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-F      H      CH.sub.3 N                                   B.351                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-F      H      CH.sub.3 CH                                  B.352                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-F      H      CH.sub.3 N                                   B.353                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-F      H      CH.sub.3 CH                                  B.354                                                                              CH.sub.3      2-F      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.355                                                                              CH.sub.3      2-F      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.356                                                                              CH.sub.3 --CH.sub.2                                                                          2-F      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.357                                                                              CH.sub.3 --CH.sub.2                                                                          2-F      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.358                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-F      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.359                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-F      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.360                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-F      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.361                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-F      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.362                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     H      CH.sub.3 N                                   B.363                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     H      CH.sub.3 CH                                  B.364                                                                              Cl--CH═CH--CH.sub.2                                                                      2-Cl     H      CH.sub.3 N                                   B.365                                                                              Cl--CH═CH--CH.sub.2                                                                      2-Cl     H      CH.sub.3 CH                                  B.366                                                                              CH.sub.3      2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.367                                                                              CH.sub.3      2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.368                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.369                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.370                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.371                                                                              CH.sub. 3 --CH.sub.2 --CH.sub.2                                                              2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.372                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.373                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.374                                                                              CH.sub.3      2-Br     H      CH.sub.3 N                                   B.375                                                                              CH.sub.3      2-Br     H      CH.sub.3 CH                                  B.376                                                                              CH.sub.3 --CH.sub.2                                                                          2-Br     H      CH.sub.3 N                                   B.377                                                                              CH.sub.3 --CH.sub.2                                                                          2-Br     H      CH.sub.3 CH                                  B.378                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Br     H      CH.sub.3 N                                   B.379                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Br     H      CH.sub.3 CH                                  B.380                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Br     H      CH.sub.3 N                                   B.381                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Br     H      CH.sub.3 CH                                  B.382                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Br     H      CH.sub.3 N                                   B.383                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Br     H      CH.sub.3 CH                                  B.384                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Br     H      CH.sub.3 N                                   B.385                                                                              CH.sub. 3 --O--CH.sub.2 --CH.sub.2 --                                                        2-Br     H      CH.sub.3 CH                                  B.386                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Br     H      CH.sub.3 N                                   B.387                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Br     H      CH.sub.3 CH                                  B.388                                                                              CH.sub.3      2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.389                                                                              CH.sub.3      2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.390                                                                              CH.sub.3 --CH.sub.2                                                                          2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.391                                                                              CH.sub.3 --CH.sub.2                                                                          2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.392                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.393                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.394                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.395                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Br     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.396                                                                              CH.sub.3      2-I      H      CH.sub.3 N                                   B.397                                                                              CH.sub.3      2-I      H      CH.sub.3 CH                                  B.398                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-I      H      CH.sub.3 N                                   B.399                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-I      H      CH.sub.3 CH                                  B.400                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-I      H      CH.sub.3 N                                   B.401                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-I      H      CH.sub.3 CH                                  B.402                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-I      H      CH.sub.3 N                                   B.403                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-I      H      CH.sub.3 CH                                  B.404                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-I      H      CH.sub.3 N                                   B.405                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-I      H      CH.sub.3 CH                                  B.406                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-I      H      CH.sub.3 N                                   B.407                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-I      H      CH.sub.3 CH                                  B.408                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-I      H      CH.sub.3 N                                   B.409                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-I      H      CH.sub.3 CH                                  B.410                                                                              CH.sub.3      2-I      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.411                                                                              CH.sub.3      2-I      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.412                                                                              CH.sub.3 --CH.sub.2                                                                          2-I      H      CH.sub. 3 --CH.sub.2 --                                                                 N                                   B.413                                                                              CH.sub.3 --CH.sub.2                                                                          2-I      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.414                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-I      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.415                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-I      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.416                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-I      H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.417                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-I      H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.418                                                                              CH.sub.3      2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.419                                                                              CH.sub.3      2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.420                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.421                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.422                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.423                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3 --CH.sub. 2 --                                                               H      CH.sub.3 CH                                  B.424                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.425                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.426                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.427                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.428                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.429                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.430                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 N                                   B.431                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 CH                                  B.432                                                                              CH.sub.3      2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.433                                                                              CH.sub.3      2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.434                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.435                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.436                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.437                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.438                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.439                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3 --CH.sub.2 --                                                                H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.440                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         3-CH.sub.3                                                                              H      CH.sub.3 N                                   B.441                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.442                                                                              Cl--CH═CH--CH.sub.2                                                                      3-CH.sub. 3                                                                             H      CH.sub.3 N                                   B.443                                                                              Cl--CH═CH--CH.sub.2                                                                      3-CH.sub.3                                                                              H      CH.sub.3 CH                                  B.444                                                                              CH.sub.3      3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.445                                                                              CH.sub.3      3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.446                                                                              CH.sub.3 --CH.sub.2                                                                          3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.447                                                                              CH.sub.3 --CH.sub.2                                                                          3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.448                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.449                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.450                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.451                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               3-CH.sub.3                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.452                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.453                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.454                                                                              Cl--CH═ CH--CH.sub.2 --                                                                  2-OCH.sub.3                                                                             H      CH.sub.3 N                                   B.455                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-OCH.sub.3                                                                             H      CH.sub.3 CH                                  B.456                                                                              CH.sub.3      2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.457                                                                              CH.sub.3      2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.458                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.459                                                                              CH.sub.3 --CH.sub.2 --                                                                       2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.460                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.461                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.462                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.463                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.464                                                                              CH.sub.3      2-CN     H      CH.sub.3 N                                   B.465                                                                              CH.sub.3      2-CN     H      CH.sub.3 CH                                  B.466                                                                              CH.sub.3 --CH.sub.2                                                                          2-CN     H      CH.sub.3 N                                   B.467                                                                              CH.sub.3 --CH.sub.2                                                                          2-CN     H      CH.sub.3 CH                                  B.468                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CN     H      CH.sub.3 N                                   B.469                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CN     H      CH.sub.3 CH                                  B.470                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CN     H      CH.sub.3 N                                   B.471                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CN     H      CH.sub.3 CH                                  B.472                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CN     H      CH.sub.3 N                                   B.473                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CN     H      CH.sub.3 CH                                  B.474                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CN     H      CH.sub.3 N                                   B.475                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CN     H      CH.sub.3 CH                                  B.476                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CN     H      CH.sub.3 N                                   B.477                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CN     H      CH.sub.3 CH                                  B.478                                                                              CH.sub.3      2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.479                                                                              CH.sub.3      2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.480                                                                              CH.sub.3 --CH.sub.2                                                                          2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.481                                                                              CH.sub.3 --CH.sub.2                                                                          2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.482                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.483                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.484                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.485                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CN     H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.486                                                                              CH.sub.3      2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.487                                                                              CH.sub.3      2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.488                                                                              CH.sub.3 --CH.sub.2                                                                          2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.489                                                                              CH.sub.3 --CH.sub.2                                                                          2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.490                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.491                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.492                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.493                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.494                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.495                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.496                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.497                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.498                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-NO.sub.2                                                                              H      CH.sub.3 N                                   B.499                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-NO.sub.2                                                                              H      CH.sub.3 CH                                  B.500                                                                              CH.sub.3      2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.501                                                                              CH.sub.3      2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.502                                                                              CH.sub.3 --CH.sub.2                                                                          2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.503                                                                              CH.sub.3 --CH.sub.2                                                                          2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.504                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.505                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.506                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  N                                   B.507                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-NO.sub.2                                                                              H      CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.508                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-Cl   CH.sub.3 N                                   B.509                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-Cl   CH.sub.3 CH                                  B.510                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-Cl   CH.sub.3 N                                   B.511                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-Cl   CH.sub.3 CH                                  B.512                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     5-Cl   CH.sub.3 N                                   B.513                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     5-Cl   CH.sub.3 CH                                  B.514                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     5-Cl   CH.sub.3 N                                   B.515                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     5-Cl   CH.sub.3 CH                                  B.516                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Cl     5-Cl   CH.sub.3 N                                   B.517                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Cl     5-Cl   CH.sub.3 CH                                  B.518                                                                              CH.sub.3      2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.519                                                                              CH.sub.3      2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.520                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.521                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.522                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.523                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.524                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.525                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.526                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.527                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.528                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.529                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.530                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.531                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.532                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.533                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.534                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Cl     5-CH.sub.3                                                                            CH.sub.3 N                                   B.535                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-Cl     5-CH.sub.3                                                                            CH.sub.3 CH                                  B.536                                                                              CH.sub.3      2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.537                                                                              CH.sub.3      2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.538                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.539                                                                              CH.sub.3 --CH.sub.2                                                                          2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.540                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.541                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.542                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.543                                                                              CH.sub.3 --(CH.sub. 2).sub.3 --                                                              2-Cl     5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.544                                                                              CH.sub.3      2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.545                                                                              CH.sub.3      2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.546                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.547                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.548                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.549                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.550                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.551                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.552                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.553                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.554                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.555                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.556                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-Cl   CH.sub.3 N                                   B.557                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-Cl   CH.sub.3 CH                                  B.558                                                                              CH.sub.3      2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.559                                                                              CH.sub.3      2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.560                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.561                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.562                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.563                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.564                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  N                                   B.565                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-Cl   CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.566                                                                              CH.sub.3      2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.567                                                                              CH.sub.3      2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.568                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.569                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             5-CH.sub. 3                                                                           CH.sub.3 CH                                  B.570                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.571                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.572                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.573                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.574                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.575                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.576                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.577                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.578                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 N                                   B.579                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 CH                                  B.580                                                                              CH.sub.3      2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.581                                                                              CH.sub.3      2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.582                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.583                                                                              CH.sub.3 --CH.sub.2                                                                          2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.584                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.585                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.586                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.587                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-OCH.sub.3                                                                             5-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.588                                                                              CH.sub.3      2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.589                                                                              CH.sub.3      2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.590                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.591                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.592                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.593                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.594                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.595                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.596                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.597                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.598                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.599                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.600                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 N                                   B.601                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 CH                                  B.602                                                                              CH.sub.3      2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.603                                                                              CH.sub.3      2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.604                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.605                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.606                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.607                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.608                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  N                                   B.609                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              6-CH.sub.3                                                                            CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.610                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.611                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.612                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.613                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.614                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.615                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.616                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.617                                                                              CH.sub.3 --(CH.sub. 2).sub.3 --                                                              2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.618                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.619                                                                              CH.sub.2 ═CH--CH.sub.2 --                                                                2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.620                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.621                                                                              CH.sub.3 --O--CH.sub.2 --CH.sub.2 --                                                         2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.622                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 N                                   B.623                                                                              Cl--CH═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 CH                                  B.624                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  N                                   B.625                                                                              CH.sub.3      2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.626                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  N                                   B.627                                                                              CH.sub.3 --CH.sub.2                                                                          2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.628                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  N                                   B.629                                                                              CH.sub.3 --CH.sub.2 --CH.sub.2                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  CH                                  B.630                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  N                                   B.631                                                                              CH.sub.3 --(CH.sub.2).sub.3 --                                                               2-CH.sub.3                                                                              5-CH(CH.sub.3).sub.2                                                                  CH.sub.3 --CH.sub.2 --                                                                  CH                                  __________________________________________________________________________

                  TABLE C                                                          ______________________________________                                         Comp. no.                                                                              R.sup.1   R.sup.2 R.sup.3                                                                            R.sup.4                                                                             R.sup.5                                                                             R.sup.6                                                                             X                                 ______________________________________                                         C.001   CH.sub.3 --                                                                              2-CH.sub.3                                                                             H   CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                            N                                 C.002   CH.sub.3 --                                                                              3-CH.sub.3                                                                             H   CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                            CH                                C.003   CH.sub.3 --CH.sub.2                                                                      2-CH.sub.3                                                                             H   CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                            N                                 C.004   CH.sub.3 --CH.sub.2                                                                      2-CH.sub.3                                                                             H   CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                            CH                                C.005   CH.sub.3  2-CH.sub.3                                                                             H   CH.sub.3                                                                            H    H    N                                 C.006   CH.sub.3  2-CH.sub.3                                                                             H   CH.sub.3                                                                            H    H    CH                                C.007   CH.sub.3  2-CH.sub.3                                                                             H   CH.sub.3                                                                            H    C.sub.2 H.sub.5                                                                     N                                 C.008   CH.sub.3  2-CH.sub.3                                                                             H   CH.sub.3                                                                            H    C.sub.2 H.sub.5                                                                     CH                                C.009   CH.sub.3  2-CH.sub.3                                                                             H   CH.sub.3                                                                            CH.sub.3                                                                            C.sub.2 H.sub.5                                                                     CH                                ______________________________________                                    

                                      TABLE D                                      __________________________________________________________________________     Comp. no.                                                                            R.sup.1             R.sup.2                                                                             R.sup.3                                                                           X                                            __________________________________________________________________________     D.001 CH.sub.3 --         H    H  CH                                           D.002 CH.sub.3 --         H    H  N                                            D.003 CH.sub.3 --         2-Cl H  CH                                           D.004 CH.sub.3 --         2-Cl H  N                                            D.005 CH.sub.3 --         2-CH.sub.3                                                                          H  CH                                           D.006 CH.sub.3 --         2-CH.sub.3                                                                          H  N                                            D.007 CH.sub.3 --         2-OCH.sub.3                                                                         H  CH                                           D.008 CH.sub.3 --         2-OCH.sub.3                                                                         H  N                                            D.009 CH.sub.3 --         3-Cl H  CH                                           D.010 CH.sub.3 --         3-Cl H  N                                            D.011 CH.sub.3 --         3-CH.sub.3                                                                          H  CH                                           D.012 CH.sub.3 --         3-CH.sub.3                                                                          H  N                                            D.013 CH.sub.3 --         3-OCH.sub.3                                                                         H  CH                                           D.014 CH.sub.3 --         3-OCH.sub.3                                                                         H  N                                            D.015 CH.sub.3 --         2-Cl 6-Cl                                                                              CH                                           D.016 CH.sub.3 --         2-Cl 6-Cl                                                                              N                                            D.017 CH.sub.3 --CH.sub.2 --                                                                             H    H  CH                                           D.018 CH.sub.3 --CH.sub.2 --                                                                             H    H  N                                            D.019 CH.sub.3 --CH.sub.2 --                                                                             2-Cl H  CH                                           D.020 CH.sub.3 --CH.sub.2 --                                                                             2-Cl H  N                                            D.021 CH.sub.3 --CH.sub.2 --                                                                             2-CH.sub.3                                                                          H  CH                                           D.022 CH.sub.3 --CH.sub.2 --                                                                             2-CH.sub.3                                                                          H  N                                            D.023 CH.sub.3 --CH.sub.2 --                                                                             2-OCH.sub.3                                                                         H  CH                                           D.024 CH.sub.3 --CH.sub.2 --                                                                             2-OCH.sub.3                                                                         H  N                                            D.025 CH.sub.3 --CH.sub.2 --                                                                             3-Cl H  CH                                           D.026 CH.sub.3 --CH.sub.2 --                                                                             3-Cl H  N                                            D.027 CH.sub.3 --CH.sub.2 --                                                                             3-CH.sub.3                                                                          H  CH                                           D.028 CH.sub.3 --CH.sub.2 --                                                                             3-CH.sub.3                                                                          H  N                                            D.029 CH.sub.3 --CH.sub.2 --                                                                             3-OCH.sub.3                                                                         H  CH                                           D.030 CH.sub.3 --CH.sub.2 --                                                                             3-OCH.sub.3                                                                         H  N                                            D.031 CH.sub.3 --CH.sub.2 --                                                                             2-Cl H  CH                                           D.032 CH.sub.3 --CH.sub.2 --                                                                             2-Cl 6-Cl                                                                              N                                            D.033 CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                                  H    6-Cl                                                                              CH                                           D.034 CH.sub.3 --CH.sub.2 --CH.sub.2 --                                                                  H    H  N                                            D.035 CH.sub.2 ═CH--CH.sub.2 --                                                                      H    H  CH                                           D.036 CH.sub.2 ═CH--CH.sub.2 --                                                                      H    H  N                                            D.037 CH.sub.3 --CH(CH.sub. 3)--                                                                         H    H  CH                                           D.038 CH.sub.3 --CH(CH.sub.3)--                                                                          H    H  N                                            D.039 HC.tbd.C--CH.sub.2 --                                                                              H    H  CH                                           D.040 HC.tbd.C--CH.sub.2 --                                                                              H    H  N                                            D.041 cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                                H    H  CH                                           D.042 cyclo-C.sub.3 H.sub.5 --CH.sub.2 --                                                                H    H  N                                            D.043 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                       H    H  CH                                           D.044 CH.sub.3 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                       H    H  N                                            D.045 CH.sub.3 --CH═CH--CH.sub.2 --                                                                  H    H  CH                                           D.046 CH.sub.3 --CH═CH--CH.sub.2 --                                                                  H    H  N                                            D.047 CH.sub.3 --(CH.sub.2).sub.5 --                                                                     H    H  CH                                           D.048 CH.sub.3 --(CH.sub.2).sub.5 --                                                                     H    H  N                                            D.049 cyclo-C.sub.6 H.sub.11 --                                                                          H    H  CH                                           D.050 cyclo-C.sub.6 H.sub.11 --                                                                          H    H  N                                            D.051 C.sub.6 H.sub.5 --CH.sub.2 --                                                                      H    H  CH                                           D.052 C.sub.6 H.sub.5 --CH.sub.2 --                                                                      H    H  N                                            D.053 4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  CH                                           D.054 4-Cl-C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  N                                            D.055 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                                         H    H  CH                                           D.056 3-CF.sub.3 --C.sub.6 H.sub.4 --CH.sub.2 --                                                         H    H  N                                            D.057 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  CH                                           D.058 4-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  N                                            D.059 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                H    H  CH                                           D.060 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --CH.sub.2 --                                                H    H  N                                            D.061 C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                              H    H  CH                                           D.062 C.sub.6 H.sub.5 --(CH.sub.2).sub.4 --                                                              H    H  N                                            D.063 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                                H    H  CH                                           D.064 C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                                H    H  N                                            D.065 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                                           H    H  CH                                           D.066 4-F--C.sub.6 H.sub.4 --CH═CH--CH.sub.2 --CH.sub.2 --                                           H    H  N                                            D.067 t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                               H    H  CH                                           D.068 t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                               H    H  N                                            D.069 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                       H    H  CH                                           D.070 t-C.sub.4 H.sub.9 O--CO--(CH.sub.2).sub.3 --                                                       H    H  N                                            D.071 Cl--CH═CH--CH.sub.2 --                                                                         H    H  CH                                           D.072 Cl--CH═CH--CH.sub.2 --                                                                         H    H  N                                            D.073 C.sub.2 H.sub.5     6-OC.sub.2 H.sub.5                                                                  H  CH                                           D.074 C.sub.2 H.sub.5     6-OC.sub.2 H.sub.5                                                                  H  N                                            D.075 CH.sub.3 --C(CH.sub.3).sub.2 --                                                                    H    H  CH                                           D.076 CH.sub.3 --C(CH.sub.3).sub.2 --                                                                    H    H  N                                            D.077 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                               H    H  CH                                           D.078 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --                                                               H    H  N                                            D.079 CH.sub.2 ═C(CH.sub.3)--CH.sub.2 --                                                             H    H  CH                                           D.080 CH.sub.2 ═C(CH.sub. 3)--CH.sub.2 --                                                            H    H  N                                            D.081 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                                    H    H  CH                                           D.082 CH.sub.3 --CH(CH.sub.3)--CH.sub.2 --CH.sub.2 --                                                    H    H  N                                            D.083 CH.sub.3 --(CH.sub.2).sub.4 --                                                                     H    H  CH                                           D.084 CH.sub.3 --(CH.sub.2).sub.4 --                                                                     H    H  N                                            D.085 2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  CH                                           D.086 2-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  N                                            D.087 3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  CH                                           D.088 3-F--C.sub.6 H.sub.4 --CH.sub.2 --                                                                 H    H  N                                            D.089 2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  CH                                           D.090 2-Cl--C.sub.6 H.sub.4 --CH.sub.2 --                                                                H    H  N                                            D.091 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                       H    H  CH                                           D.092 3,4-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                       H    H  N                                            D.093 2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                       H    H  CH                                           D.094 2,6-Cl.sub.2 --C.sub.6 H.sub.3 --CH.sub.2 --                                                       H    H  N                                            D.095 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                           H    H  CH                                           D.096 C.sub.6 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                           H    H  N                                            D.097 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                                H    H  CH                                           D.098 C.sub.6 H.sub.5 --CH═CH--CH.sub.2 --CH.sub.2 --                                                H    H  N                                            D.099 4-Cl--C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                          H    H  CH                                           D.100 4-Cl--C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2 --                                          H    H  N                                            D.101 4-CF.sub.3 --C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                      H-   H  CH                                           D.102 4-CF.sub.3 --C.sub.6 H.sub.5 --CH.sub.2 --CH═CH--CH.sub.2                                      H-   H  N                                            __________________________________________________________________________

                  TABLE E                                                          ______________________________________                                         Comp. no.                                                                              R.sup.1          R.sup.2  R.sup.3                                      ______________________________________                                         E.001   CH.sub.3         2-CH.sub.3                                                                              5-CH.sub.3                                   E.002   CH.sub.3 CH.sub.2 --                                                                            2-CH.sub.3                                                                              5-CH.sub.3                                   E.003   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                   E.004   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-CH.sub.3                                                                              5-CH.sub.3                                   E.005   HC.tbd.C--CH.sub.2 --                                                                           2-CH.sub.3                                                                              5-CH.sub.3                                   E.006   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                   E.007   CH.sub.3 --CH═CH--CH.sub.2                                                                  2-CH.sub.3                                                                              5-CH.sub.3                                   E.008   C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                        2-CH.sub.3                                                                              5-CH.sub.3                                   E.009   CH.sub.3         2-CH.sub.3                                                                              2-Cl                                         E.010   CH.sub.3 CH.sub.2 --                                                                            2-CH.sub.3                                                                              2-Cl                                         E.011   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-CH.sub.3                                                                              2-Cl                                         E.012   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-CH.sub.3                                                                              2-Cl                                         E.013   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              2-Cl                                         E.014   CH.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                       2-CH.sub.3                                                                              2-Cl                                         E.015   CH.sub.3         2-CH.sub.3                                                                              5-isopropyl                                  E.016   CH.sub.3 CH.sub.2 --                                                                            2-CH.sub.3                                                                              5-isopropyl                                  E.017   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-isopropyl                                  E.018   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-CH.sub.3                                                                              5-isopropyl                                  E.019   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-isopropyl                                  E.020   CH.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                       2-CH.sub.3                                                                              5-isopropyl                                  E.021   CH.sub.3         2-Cl     5-Cl                                         E.022   CH.sub.3 CH.sub.2 --                                                                            2-Cl     5-Cl                                         E.023   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-Cl     5-Cl                                         E.024   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-Cl     5-Cl                                         E.025   HC.tbd.C--CH.sub.2 --                                                                           2-Cl     5-Cl                                         E.026   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-Cl     5-Cl                                         E.027   C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                        2-Cl     5-Cl                                         E.028   CH.sub.3         2-F      H                                            E.029   CH.sub.3 CH.sub.2 --                                                                            2-F      H                                            E.030   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-F      H                                            E.031   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-F      H                                            E.032   HC.tbd.C--CH.sub.2 --                                                                           2-F      H                                            E.033   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-F      H                                            E.034   CH.sub.3         2-Cl     5-CH.sub.3                                   E.035   CH.sub.3 CH.sub. 2 --                                                                           2-Cl     5-CH.sub.3                                   E.036   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-Cl     5-CH.sub.3                                   E.037   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-Cl     5-CH.sub.3                                   E.038   HC.tbd.C--CH.sub.2 --                                                                           2-Cl     5-CH.sub.3                                   E.039   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-Cl     5-CH.sub.3                                   E.040   CH.sub.3         2-CN     H                                            E.041   CH.sub.3 CH.sub.2 --                                                                            2-CN     H                                            E.042   CH.sub.3 (CH.sub.2).sub.4 --                                                                    2-CH.sub.3                                                                              5-CH.sub.3                                   E.043   CH.sub.3 (CH.sub.2).sub.5 --                                                                    2-CH.sub.3                                                                              5-CH.sub.3                                   E.044   C.sub.6 H.sub.5 --CH.sub.2 --                                                                   2-CH.sub.3                                                                              5-CH.sub.3                                   E.045   t-C.sub.4 H.sub.9 O--CO--CH.sub.2 --                                                            2-CH.sub.3                                                                              5-CH.sub.3                                   E.046   Cl--CH═CH--CH.sub.2 --                                                                      2-CH.sub.3                                                                              5-CH.sub.3                                   E.047   CH.sub.3 O--CH.sub.2 --CH.sub.2 --                                                              2-CH.sub.3                                                                              5-CH.sub.3                                   E.048   CH.sub.3 CH.sub.2 CH.sub.2 --                                                                   2-CH.sub.3                                                                              H                                            E.049   CH.sub.3 CH.sub.2 CH.sub.2 CH.sub.2 --                                                          2-CH.sub.3                                                                              H                                            E.050   CH.sub.3 (CH.sub.2).sub.4 --                                                                    2-CH.sub.3                                                                              H                                            E.051   CH.sub.3 (CH.sub.2).sub.5 --                                                                    2-CH.sub.3                                                                              H                                            E.052   CH.sub.3 (CH.sub.2).sub.6 --                                                                    2-CH.sub.3                                                                              H                                            E.053   HC.tbd.C--CH.sub.2 --                                                                           2-CH.sub.3                                                                              H                                            E.054   CH.sub.2 ═CH--CH.sub.2 --                                                                   2-CH.sub.3                                                                              H                                            E.055   CH.sub.3 --CH═CH--CH.sub.2 --                                                               2-CH.sub.3                                                                              H                                            E.056   C.sub.2 H.sub.5 --CH.sub.2 --CH.sub.2 --                                                        2-CH.sub.3                                                                              H                                            E.057   CH.sub.3 O--CH.sub.2 --CH.sub.2 --                                                              2-CH.sub.3                                                                              H                                            E.058   C.sub.6 H.sub.5 --CH.sub.2 --                                                                   2-CH.sub.3                                                                              H                                            E.059   Cl--CH═CH--CH.sub.2 --                                                                      2-CH.sub.3                                                                              H                                            E.060   t-C.sub.4 H.sub.9 O--CH--CH.sub.2 --                                                            2-CH.sub.3                                                                              H                                            E.061   cyclo-C.sub.6 H.sub.11 --                                                                       2-CH.sub.3                                                                              H                                            E.062   (CH.sub.3).sub.2 --CH--                                                                         2-CH.sub.3                                                                              H                                            E.063   t-butyl-         2-CH.sub.3                                                                              H                                            E.064   (CH.sub.3).sub.2 --CH--CH.sub.2 --                                                              2-CH.sub.3                                                                              H                                            E.065   (CH.sub.3).sub.2 --CH--                                                                         2-CH.sub.3                                                                              5-CH.sub.3                                   E.066   t-butyl          2-CH.sub.3                                                                              5-CH.sub.3                                   E.067   (CH.sub.3).sub.2 --CH--CH.sub.2 --                                                              2-CH.sub.3                                                                              5-CH.sub.3                                   ______________________________________                                    

In general terms, the novel compounds I are extremely effective on a broad spectrum of phytopathogenic fungi, in particular those from the class consisting of the Ascomycetes and Basidiomycetes. Some of them have a remarkably high systemic mobility and action after application to the soil and particularly to foliage.

The fungicidal compounds are of particular interest for controlling a large number of fungi in various crops or their seeds, especially wheat, rye, barley, oats, rice, Indian corn, lawns, cotton, soybeans, coffee, sugar cane, fruit and ornamentals in horticulture and viticulture, and in vegetables such as cucumbers, beans and cucurbits.

The novel compounds are particularly useful for controlling the following plant diseases:

Erysiphe graminis in cereals,

Erysiphe cichoracearum and Sphaerotheca fuliginea in cucurbits,

Podosphaera leucotricha in apples,

Uncinula necator in vines,

Puccinia species in cereals,

Rhizoctonia solani in cotton,

Ustilago species in cereals and sugar cane,

Venturia inaegualis (scab) in apples,

Helminthosporium species in cereals,

Septoria nodorum in wheat,

Botrytis cinerea (gray mold) in strawberries and grapes,

Cercospora arachidicola in groundnuts,

Pseudocercosporella herpotrichoides in wheat and barley,

Pyricularia oryzae in rice,

Phytophthora infestans in potatoes and tomatoes,

Fusarium and Verticillium species in various plants,

Plasmopara viticola in grapes,

Alternaria species in fruit and vegetables.

The compounds I are applied by spraying or dusting the plants with the active ingredients, or treating the seeds of the plants with the active ingredients. They may be applied before or after infection of the plants or seeds by the fungi.

The novel substances can be converted into conventional formulations such as solutions, emulsions, suspensions, dusts, powders, pastes and granules. The application forms depend entirely on the purposes for which they are intended; they should at all events ensure a fine and uniform distribution of the active ingredient. The formulations are produced in known manner, for example by extending the active ingredient with solvents and/or carriers, with or without the use of emulsifiers and dispersants; if water is used as solvent, it is also possible to employ other organic solvents as auxiliary solvents. Suitable auxiliaries for this purpose are solvents such as aromatics (e.g., xylene), chlorinated aromatics (e.g., chlorobenzenes), paraffins (e.g., crude oil fractions), alcohols (e.g., methanol, butanol), ketones (e.g., cyclohexanone), amines (e.g., ethanolamine, dimethylformamide), and water; carriers such as ground natural minerals (e.g., kaolins, aluminas, talc and chalk) and ground synthetic minerals (e.g., highly disperse silica and silicates); emulsifiers such as nonionic and anionic emulsifiers (e.g., polyoxyethylene fatty alcohol ethers, alkyl sulfonates and aryl sulfonates); and dispersants such as lignin-sulfite waste liquors and methylcellulose.

The fungicides generally contain from 0.1 to 95, and preferably from 0.5 to 90, wt % of active ingredient. The application rates are from 0.02 to 3 kg or more of active ingredient per hectare,. depending on the type of effect desired.

When the active ingredients are used for treating seed, application rates of from 0.001 to 50, and preferably from 0.01 to 10, g per kg of seed are generally required.

When the agents according to the invention are used as fungicides, they may be employed together with other active ingredients, e.g., herbicides, insecticides, growth regulators, other fungicides and fertilizers.

When admixed with other fungicides, the spectrum of fungicidal action is in many instances increased.

The compounds of the formula IA are suitable for effectively combating pests such as insects, arachnids and nematodes. They may be used as pesticides in crop protection and in the hygiene, stores protection and veterinary sector.

Examples of injurious insects belonging to the Lepidoptera order are Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholita funebrana, Grapholita molesta, Heliothis armigera, Hellothis virescens, Hellothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keifferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Phyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera irugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni and Zeiraphera canadensis.

Examples from the Coleoptera order are Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Ceuthorrhynchus assimilis, Ceuthorrynchus napi, Chaetocnema tibiaIls, Conoderus vespertinus, Crioceris asparagi, Diabrotica longicornis, Diabrotica 12-punctara, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus and Sitophilus granaria.

Examples from the Diptera order are Aedes aegypti, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Contarinia sorghicola, Cordylobia anthopophaga, Culex piplens, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Fannia canicularis, Gasterophilus intestinalis, Glossina morsitans, Haematobia irritans, Haplodiplosis eguestris, Hylemyia platura, Hypoderma lineata, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Oscinella frit, Pegomya hyoscyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletis cerasi, Rhagoletis pomonella, Tabanus bovinus, Tipula oleracea and Tipula paludosa.

Examples from the Thysanoptera order are Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi and Thrips tabaci.

Examples from the Hymenoptera order are Athalia rosae, Atta cephalotes, Atta sexdens, Atta texana, Hoplocampa minuta, Hoplocampa testudinea, Monomoriumpharaonis, Solenopsis geminata and Solenopsis invicta.

Examples from the Heteroptera order are Acrosternum hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis and Thyanta perditor.

Examples from the Homoptera order are Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis pomi, Aphis sambuci, Bemisia tabaci, Brachycaudus cardui, Brevicoryne brassicae, Cerosipha gossypii, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Empoasca fabae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megoura viciae, Metopolophiumdirhodum, Myzodes persicae, Myzus cerasi, Nephotettix cincticeps, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphummaidis, Sappahis mali, Schizaphis graminum, Schizoneura lanuginosa, Trialeurodes vaporariorum and Viteus vitifolii.

Examples from the Isoptera order are Calotermes flavicollis, Leucotermes flavipes, Retuculitermes lucifugus and Termes natalensis.

Examples from the Orthoptera order are Acheta domestica, Blatta orientalis, Blattella germanica, Forficula auricularia, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femur-rubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplaneta americana, Schistocerca americana, Schistocerca peregrina, Stauronotus maroccanus and Tachycines asynamorus.

Examples from the Acarina order are Amblyomma americanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Brevipalpus phoenicis, Bryobia praetiosa, Dermacentor silvarum, Eotetranychus carpini, Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Metatetranychus (Panonychus) ulmi, Ornithodorus moubata, Otobins megnini, Paratetranychus pilosus, Dermanyssus gallinae, Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae.

Examples from the nematodes class are root-knot nematodes, e.g., Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica, Zysten bildende Nematoden, z.B. Globodera rostochiensis, Heterodera avenae, Heterodera glycinae, Heterodera schachtii, Heterodera trifolii, Stock- und Blattalchen, z.B. Belonolaimus longicaudatus, Ditylenchus destructor, Ditylenchus dipsaci, Heliocotylenchus multicinctus, Longidorus elongatus, Radopholus similis, Rotylenchus robustus, Trichodorus primitivus, Tylenchorhynchus claytoni, Tylenchorhynchus dubius, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus and Pratylenchus goodeyi.

The active ingredients may be applied for instance as such, or in the form of formulations or application forms prepared therefrom, e.g., directly sprayable solutions, powders, suspensions, dispersions, emulsions, oil dispersions, pastes, dusts, broadcasting agents, or granules by spraying, atomizing, dusting, broadcasting or watering. The forms of application depend entirely on the purpose for which the agents are being used, but they must ensure as fine a distribution of the active ingredients according to the invention as possible.

The active ingredient concentrations in the finished formulations may vary within wide limits, but are generally from 0.0001 to 10, and preferably from 0.01 to 1%.

The active ingredients may also be successfully used in the ultra-low-volume (ULV) method, where it is possible to apply formulations containing more than 95wt % of active ingredient, or the active ingredient without any additives at all.

When the active ingredients are used for combating pests in the open, the application rates are from 0.1 to 2.0, and preferably from 0.2 to 1.0, kg/ha.

For the preparation of solutions, emulsions, pastes and oil dispersions to be sprayed direct, mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, further coal-tar oils, and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons such as toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, methanol, ethanol, propanol, butanol, cyclohexanol, cyclohexanone, chlorobenzene, isophorone, etc., and strongly polar solvents such as N,N-dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone, water, etc. are suitable.

Aqueous formulations may be prepared from emulsion concentrates, pastes, oil dispersions, wettable powders or water-dispersible granules by adding water. To prepare emulsions, pastes and oil dispersions the ingredients as such or dissolved in an oil or solvent may be homogenized in water by means of wetting or dispersing agents, adherents or emulsifiers. Concentrates which are suitable for dilution with water may be prepared from active ingredient, wetting agent, adherent, emulsifying or dispersing agent and possibly solvent or oil.

Examples of surfactants are: alkali metal, alkaline earth metal. and ammonium salts of aromatic sulfonic acids, e.g., ligninsulfonic acid, phenolsulfonic acid, naphthalenesulfonic acid and dibutylnaphthalenesulfonic acid, and of fatty acids, alkyl and alkylaryl sulfonates, and alkyl, lauryl ether and fatty alcohol sulfates, and salts of sulfated hexadecanols, heptadecanols, and octadecanols, salts of fatty alcohol glycol ethers, condensation products of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensation products of naphthalene or naphthalenesulfonic acids with phenol and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, ethoxylated octylphenol and ethoxylated nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignin-sulfite waste liquors and methyl cellulose.

Powders, dusts and broadcasting agents may be prepared by mixing or grinding the active ingredients with a solid carrier.

The formulations generally contain from 0.01 to 95, and preferably from 0.1 to 90, wt % of active ingredient. The active ingredients are used in a purity of from 90 to 100, and preferably from 95 to 100% (according to the NMR spectrum).

Granules, e.g., coated, impregnated or homogeneous granules, may be prepared by bonding the active ingredients to solid carriers. Examples of solid carriers are mineral earths such as silicic acids, silica gels, silicates, talc, kaolin, attapulgus clay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, and ureas, and vegetable products such as grain meals, bark meal, wood meal, and nutshell meal, cellulosic powders, etc.

Examples of formulations are as follows:

Granules, e.g., coated, impregnated or homogeneous granules; they may be preparedby bonding the active ingredients to solid carriers. Examples of solid carriers are mineral earths such as silicic acids, silica gels, silicates, talc, kaolin, attapulgus clay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, and ureas, and vegetable products such as grain meals, bark meal, wood meal, and nutshell meal, cellulosic powders, etc.

The active ingredients may also be applied together with other crop protection agents such as herbicides, fungicides other pesticides and bactericides. These agents may be added to the agents according to the invention in a weight ratio of from 1:10 to 10:1, if desired immediately prior to use (tankmix).

In these application forms, the agents according to the invention may also be present together with other active ingredients, for example herbicides, insecticides, growth regulators, and fungicides, and may furthermore be mixed and applied together with fertilizers. Admixture with other fungicides frequently results in a greater fungicidal action spectrum.

Examples demonstrating the action on injurious fungi

For comparison purposes the following compounds were used: 2-(2'-methylphenoxymethyl)-phenylglyoxylic acid methyl ester-O-methyloxime (A) having the formula ##STR11## and

2-(2'-methyl-4'-(methoximinoeth-1"-yl)-phenoxymethyl)phenylglyoxylic acid methyl ester-O-methyloxime (B) having the formula ##STR12##

A.1 Action on Plasmopara

Leaves of potted vines of the Muller-Thurgau variety were sprayed with aqueous suspensions containing (dry basis) 80% of active ingredient and 20% of emulsifier. To assess the duration of action, the plants were set up, after the sprayed-on layer had dried, for 8 days in the greenhouse. Then the leaves were infected with a zoospore suspension of Plasmopara viticola. The plants were first placed for 48 hours in a water vapor-saturated chamber at 24° C. and then in a greenhouse for 5 days at from 20° to 30° C. To accelerate and intensify the sporangiophore discharge, the plants were then again placed in the moist chamber for 16 hours. The extent of fungus attack was then assessed on the undersides of the leaves.

    ______________________________________                                                 Percentage leaf attack after applying aqueous                          Active in-                                                                             formulations containing . . . ppm of active                            gredient                                                                               ingredient                                                             no.     60 ppm                   15 ppm                                        ______________________________________                                         I.007   0                        0                                             I.011   0                        0                                             Untreated            65                                                        ______________________________________                                    

A.2 Action on wheat brown rust

Leaves of pot-grown wheat seedlings of the "Kanzler" variety were dusted with spores of brown rust (Puccinia recondita). The pots were then placed for 24 hours at 20° to 22° C. in a high-humidity (90-95%) chamber. During this period the spores germinated and the germ tubes penetrated the leaf tissue. The infected plants were then sprayed to runoff with aqueous liquors containing (dry basis) 80% of active ingredient and 20% of emulsifier. After the sprayed-on layer had dried, the plants were set up in the greenhouse at 20° to 22° C. and a relative humidity of 65 to 70%. The extent of rust fungus spread on the leaves was assessed after 8 days.

    ______________________________________                                                 Percentage leaf attack after application of                            Active in-                                                                             aqueous formulations containing . . . ppm of                           gredient                                                                               active ingredient                                                      no.     60 ppm                   15 ppm                                        ______________________________________                                         I.007   0                        0                                             I.011   0                        0                                             Untreated            70                                                        ______________________________________                                    

A. 3 Action on bean rust

The undersides of leaves of bush beans of the "Fori" variety were uniformly sprayed with an aqueous spore suspension of bean rust (Uromyces appendiculatus). The plants were then kept for 24 hours in a high-humidity climatic cabinet at 19° C. and then set up in the greenhouse at 22° to 25° C. After 2 to 3 days the lower (basal) half of the upper side of the leaves was sprayed with the active ingredients. Fungus spread was assessed 10 to 12 days after spraying. As a result of the temporal and spatial separation of leaf treatment with the spores and leaf treatment with the active ingredients, there is no direct contact between fungus and active ingredient; consequently, the fungicidal action must have been preceded by active ingredient uptake and migration (systemic transport) in the leaf. By examining the various leaf zones it is possible to ascertain whether translaminar or apical movement of the candidate active ingredients has taken place in the leaf.

The results of the experiment show that, after treatment with a spray liquor containing 50 ppm of active ingredient, active ingredients nos. I.003, I.007 and I.014 had a fungicidal action on the leaf undersides and in part on the uncreated portion of the bean leaves, whereas the prior art comparative compounds A and B had no fungicidal action.

Use examples demonstrating the action on pests

The action of compounds of the general formula IA on pests from the class of insects, mites and nematodes may be demonstrated by the following experiments:

The active ingredients were formulated

a) as a 0.1% strength solution in acetone, or

b) as a 10% strength emulsion in a mixture of 70wt % of cyclohexanol, 20wt % of Nekanil®LN (Lutenso® AP6, a spreader-sticker with an emulsifying and dispersing action based on ethoxylaced alkylphenols) and 10wt % of EmulphorI EL (Emulan®EL, an emulsifier based on ethoxylated fatty alcohols)

and diluted to the desired concentration with acetone in the case of a) and with water in the case of b).

Upon conclusion of the experiments the lowest concentration was determined at which the compounds, compared with the uncreated controls, achieved 80% inhibition or kill (action threshold or minimum concentration).

B.1 Aphis fabae, contact action

Bush beans (Vicia faba) under heavy louse attack were treated with aqueous formuations of the active ingredients.

The kill rate was determined after 24 hours.

In this test, compounds nos. I.007, I.011, I.015, I.003, I.001, I.017, I.058, I.086, I.096 and I.029 exhibited action thresholds of from 200 to 1000 ppm.

B.2 Nephotettix cincticeps, contact action

Circular filter papers were treated with aqueous formulations of the active ingredients; 5 adult leafhoppers were then placed on the filter papers.

the kill rate was determined after 24 hours.

In this test, compounds nos. I.007, I.011, I.014, I.015, I.003, I.002, I.004, I.017, I.117, I.307, I.192, I.193, I.195 and I.201 exhibited action thresholds of from 0.4 to 0.1 mg.

B.3 Prodenia litura, breeding experiment

Five caterpillars in the development stage L3 (10-12 mm) were placed on a standard nutrient medium (3.1 liters of water, 80 g of agar, 137 g of brewer's yeast, 515 g of cornflour, 130 g of wheat germ, and conventional additives and vitamins (20 g of Wessons salt, 5 g of Nipagin, 5 g of sorbic acid, 10 g of cellulose powder, 18 g of ascorbic acid, 1 g of Lutavit® blend (vitamin) and 5 ml of alcoholic biotin solution)) which had previously been wetted with aqueous formulations of the active ingredients.

Observation extended up to emergence of the moths in a control experiment without active ingredient.

In this test, compounds nos. I.003, I.014, I.015, I.017, I.057, I.064, I.068, I.076, I.100, I.108, I.109, I.112, I.119 and I.079 exhibited action thresholds of from 200 to 0.1 ppm.

B.4 Agrotis ypsilon, contact action

Corn leaves were dipped for 3 seconds in aqueous formulations of the active ingredients and placed, after excess liquid had been allowed to drip off, on circular filter papers in a Petri dish 12 cm in diameter. 5 caterpillars in the third and fourth larval stages (about 15 mm long) were placed in each dish.

The action in % feeding inhibition and % kill was assessed after 24 and 48 hours.

In this test, compounds nos. I.060, I.070, I.086, I.090, I.096, I.117, I.121, I.129, I.140, I.177, I.307, I.189, I.190, I.191, I.192, I.193, I.195, I.201 and I.213 exhibited a threshold action of from 10 to 1000 ppm.

B.5 Sitophilus granaria, contact action

The bottoms of experimental vessels were treated with acetonic solutions of the active ingredients. After the acetone 10 had evaporated, about 50 weevils were introduced into each dish.

After 4 hours, the weevils were transferred to cardboard dishes, which were then placed in the experimental vessels.

The action was determined after 24 hours in percentage kill. Weevils unable to leave the cardboard dishes were considered to be dead or heavily damaged.

In this test, compound no. I.115 exhibited an action threshold of 1 mg.

B.6 Musca domestica, contact experiment

The bottoms of experimental vessels were wetted with acetonic solutions of the active ingredients and, after the solvent had evaporated, 10 flies were placed in each vessel.

The kill rate was determined after 4 hours.

In this test, compounds nos. I.064, I.071, I.077, I.078, I.080, I.083, I.085, I.098, I.100, I.103, I.106, I.111, I.115, I.117, I.126, I.127, I.130, I.133, I.309 and I.184 exhibited an action threshold of from 0.01 to 2 mg.

B.7 Musca domestica, breeding experiment

25 ml of a dry feed mix (1 kg of bran, 250 g of yeast powder, 35 g of fish meal) was mixed with the active ingredients and 25 ml of a milk-sugar solution (1 liter of milk and 42 g of sugar) and 20 larvae of the first development stage were then placed on it.

The kill rate was determined after the larvae in a control experiment had hatched.

In this test, compound no. I.064 exhibited an action threshold of 40 ppm.

B.8 Prodenia litura, contact experiment

Circular filter papers 9 cm in diameter were treated with 1 cm³ of aqueous formulations of the active ingredients and then placed in a plastic Petri dish 94 mm in diamter. 5 Prodenia caterpillars L3 were then introduced into each dish and the dishes were closed. Assessment took place after 24 hours.

In this test, compounds nos. I.098, I.100, I.102, I.106, I.111, I.115 and I.184 exhibited an action theshold of from 0.1 to 1 mg.

B.9 Prodenia litura, breeding experiment

Five caterpillars in the development stage L3 (10-12 mm) were placed on a standard nutrient medium (3.1 liters of water, 80 g of agar, 137 g of brewer's yeast, 515 g of cornflour, 130 g of wheat germ, and conventional additives and vitamins (20 g of Wessons salt, 5 g of Nipagin, 5 g of sorbic acid, 10 g of cellulose powder, 18 g of ascorbic acid, 1 g of Lutavit® blend (vitamin) and 5 ml of alcoholic biotin solution)) which had previously been wetted with aqueous formulations of the active ingredients.

Observation extended up to emergence of the moths in a control experiment without active ingredient.

In this test, compounds nos. I.128, I.272, I.292, I.293, I.307 and I.310 exhibited an action threshold of from 1 to 1000 ppm.

B.10Plutella maculipennis, contact action

Leaves of young cabbage plants were wetted with aqueous solutions of the active ingredients and then placed on moistened filter papers. 10 caterpillars in the fourth development stage were then placed on the leaves prepared in this way.

The kill rate was determined after 48 hours.

In this test, compounds nos. I.064, I.065, I.068, I.079, I.081, I.084, I.086, I.088, I.090, I.117 and I.130 exhibited an action threshold of from 200 to 1000 ppm.

B.11Aedes aegypti, breeding experiment

Plastic beakers 8 cm in diameter and holding 250 ml were filled with 200 ml of tapwater of 23° C.; 30-40 Aedes larvae in the third to fourth larval stage were then introduced into each beaker. The candidate compounds are then added as aqueous emulsions or suspensions to the vessels and the kill rate is determined after 24 hours. Breeding is then continued until the mosquitoes emerge. The room temperature is 25° C.

In this test, compound no. I.128 exhibited an action threshold of 0.1 ppm. 

We claim:
 1. A substituted oxime ether of the formula I ##STR13## where R¹ is C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₄ -alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl, C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, aryl-C₁ -C₆ -alkyl, hetaryl-C₁ -C₆ -alkyl, aryl-C₃ -C₆ -alkenyl or aryloxy-C₁ -C₆ -alkyl, where the aromatic or heteroaromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₃ -C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ or C₂ -haloalkoxy, halogen, aryl or aryloxy,R² and R³ are identical or different and are each hydrogen, C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro, R⁴ is hydrogen, C₁ -C₆ -alkyl, C₃ -C₆ -cycloalkyl, C₁ -C₂ -haloalkyl or aryl, where the aromatic ring is unsubstituted or substituted by one or more of the following radicals: C₁ -C₄ -alkyl, C₁ - or C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ - or C₂ -haloalkoxy, halogen, cyano or nitro, R⁵ and R⁶ are identical or different and are each hydrogen or C₁ -C₄ -alkyl and X is CH or N.
 2. A fungicidal composition comprising an inert carrier and a fungicidal amount of a substituted oxime ether of the formula I as claimed in claim
 1. 3. A method for controlling fungi, wherein the fungi or the materials, plants or seeds threatened by fungal attack or the soil is or are treated with a fungicidal amount of a substituted oxime ether of the formula I as claimed in claim
 1. 4. A pesticidal composition effective against insects, arachnids or nematodes comprising inert additives and a pesticidal amount of a compound of the formula I as claimed in claim
 1. 5. A compound of the formula I as claimed in claim 1, where R¹, R² (in the 2-position), R⁴ and R⁵ are each methyl, R³ and R⁵ are each hydrogen, X is N and the oximinoethyl radical is in the 4-position.
 6. A compound of the formula I as claimed in claim 1, where R¹, R² (in the 2-position), R⁴ and R⁶ are each methyl, R³ and R⁵ are each hydrogen, X is CH and the oximinoethyl radical is in the 4-position.
 7. A compound of the formula I as claimed in claim 1, where R¹ is methyl, R² in the 2-position is methyl, R⁴ is cyclopropyl, R⁶ is methyl, R³ and R⁵ are each hydrogen, X is N and the oximino radical is in the 4-position.
 8. A compound of the formula I as claimed in claim 1, where R¹ is methyl, R² in the 2-position is methyl, R⁴ is trifluoromethyl, R⁶ is methyl, R³ and R⁵ are each hydrogen, X is N and the oximino radical is in the 4-position. 